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Sarcosine Supplement
Sarcosine Supplement
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Sarcosine Supplement
Brain nutrition
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$27.00 In Stock

Sarcosine supports emotional well-being and provides brain nutrition.

  • Supports the body in adapting better to life's challenges
  • Facilitates motivation and decision-making
  • Aids cognition, including memory, rate of recall and development of learning capacity
100 Veg. Caps.
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Sarcosine molecule and molecular structure

Sarcosine Supplement

Our sarcosine supplement provides nootropic effects and helps support emotional well-being. As with any nootropic, it helps the body adapt better to life's challenges, facilitates motivation and decision-making and aids cognitive and neurosensory processes as a whole.

On this page, we will look closer at what sarcosine is, how it affects the brain and what benefits you may receive by taking it on a regular basis. You will also learn about potential sarcosine side effects, as well as the appropriate way to take this high-quality supplement.

What is Sarcosine?

Sarcosine (N-methylglycine) is a methyl derivative of the amino acid glycine. It is found in egg yolk, turkey, ham, vegetables and legumes. It was first isolated and named by the German chemist Justus von Liebig in the mid-19th century.

Sarcosine is naturally present in the body in muscles and various tissues via the enzyme glycine dehydrogenase. It is formed from choline intake and from the metabolism of methionine and is then broken down into glycine, an important constituent of protein.

Sarcosine contains a mild, sweet flavor that is quite distinct. In fact, it was used as the main ingredient in many types of toothpaste for several decades. Studies even show that a particular form of sarcosine may even prevent cavities. It also creates the foaming action that people look for in a toothpaste.

However, toothpaste is no longer the primary purpose of sarcosine. With extensive research, many sarcosine supplement benefits were found related to mental health. There's been a connection discovered between sarcosine and schizophrenia, as well as sarcosine and depression.

Sarcosine may also aid memory and learning, as it’s been shown to support brain health, in addition to mental health. Let's take a closer look at the science behind this supplement.

What Are Sarcosine's Effects on the Brain?

The human brain is by far the most complex organ in the body. It weighs only three pounds, but it’s responsible for interpreting senses, initiating body movement and controlling behavior.

Over time, the deterioration of the brain can lead to major neurological problems, including confusion and dementia. And, when left untreated, the brain's nerves and tissue can deteriorate completely.

Sarcosine affects the brain because of its relationship to GlyT1, a transporter that moves glycine and D-serine to the cells. With this transportation, the body's levels of D-serine and glycine increase.

D-serine is an amino acid located in the brain. It activates neurotransmitter receptors called NMDA receptors, which are needed for the formation of new synapses and are vital for learning and memory.

Glycine is an amino acid the body needs for protein creation. These proteins are used for tissue growth and maintenance. They also create enzymes and hormones. Studies show this is one of three amino acids needed to make glutathione, an antioxidant that protects your cells from oxidative damage.

Research shows that glycine also calms the brain, allowing you to fall asleep easier and possibly sleep for longer. Furthermore, glycine is one of the main amino acids found in collagen, a core structural protein found in connective tissue needed for bone, ligament, skin, cartilage and tendon health.

With the role sarcosine plays in promoting glycine and D-serine production, it's no wonder there are so many benefits from taking a sarcosine dietary supplement. We will take a closer look at what this supplement can be used for and the connection between sarcosine and cognition and schizophrenia.

Sarcosine Benefits

What benefits can you expect to receive from sarcosine? This supplement is essential for muscle synthesis and composition, but it is also the principal metabolic source of glutathione, creatine and serine. Apart from its critical role in certain metabolic processes, it has three main properties:

  • It naturally increases levels of testosterone when combined with D-aspartic acid. By encouraging the production of GnRH (gonadotropin-releasing hormone) by the hypothalamus, it boosts the release of FSH and LH, which in turn stimulates the testes to produce more testosterone.
  • It inhibits the transport of type 1 glycine (GlyT-1), and. therefore, increases glycine concentrations in the brain — activating N-methyl-D-aspartate (NMDA) receptors.
  • According to clinical trials, it has nootropic effects and combats symptoms of depression.
  • In addition, an ongoing avenue of investigation shows that sarcosine supplementation, at a dose of 2,000 mg a day, may even reduce symptoms of schizophrenia when used alongside existing treatments. Promising results show reductions in cognitive symptoms and depression.
  • It may aid cognition and mental processes, including memory and recall rate, as well as the capacity for learning. These effects may be linked to its impact on glycine receptors in the brain.

Sarcosine capsules constitute a new nootropic, along with other supplements, such as Noopept and AFA extract, available to buy at Supersmart. Supplementation of sarcosine benefits healthy adults just as it does those with Alzheimer's disease and who are undergoing what can be an aggressive treatment plan to alleviate degenerative cognition problems.

Sarcosine Side Effects

Before you buy a sarcosine supplement, you need to understand the potential side effects. While sarcosine supplements are considered safe in most situations, there are times when it's best to seek professional guidance from your healthcare practitioner before starting to take them daily.

We also recommend researching the sarcosine tablets you plan to purchase. You should only purchase supplements from a highly-rated sarcosine supplement seller.

Additionally, use caution when taking a sarcosine nutritional supplement with any other medications or supplements. It's always best to review the supplements and medications you are taking with your doctor to avoid any negative reactions between the medications and supplements you take.

If you suffer from any underlying conditions, you should consult your healthcare professional about which supplements are best for you. While some studies suggest sarcosine for patients with schizophrenia may be effective, you should always consult a healthcare professional before taking it.

As with any new supplement, watch for signs of interactions once you begin your new regimen. If anything out of the ordinary occurs stop using immediately and talk with your doctor. You may notice side effects when starting a new supplement. And, although some could be considered normal, it's always best to talk with someone that understands your health care needs to determine that.

Daily dose: 6 capsules
Number of doses per pack: 16
Amount per dose
Sarcosine 3 000 mg
Other ingredients: Acacia gum, rice flour.
Directions for use

Sarcosine Dosage

Our vegetarian sarcosine capsules contain 500 mg per capsule. We recommend taking between 1,500 mg and 3,000 mg a day, or three to six capsules, split between two doses.

In one study, schizophrenia patients were given two grams of sarcosine each day, consisting of two 500 mg capsules, twice a day. Never exceed the recommended dose without consulting your doctor.

And, because sarcosine naturally occurs in some foods, you should be aware of how much you take while eating an excessive amount of legumes, turkey and egg yolks.

Unless your physician advises you otherwise, you can take sarcosine with your other medications or supplements. You’re also able to take sarcosine with food and on an empty stomach.

One container of Supersmart’s sarcosine supplement includes 96 capsules. If you took six a day, you would have a 16-day supply. We pride ourselves on using minimal ingredients in our supplements, which is why the only other ingredients you will find with this pill are acacia gum and rice flour.

To maintain its integrity, you should keep sarcosine away from heat and humidity. We also recommend speaking with a medical professional if you are pregnant, nursing or struggling with any other healthcare concerns because you start taking sarcosine, or any other nutritional supplement from Supersmart.

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Op 2 gram sarcosine per dag: goede stemming. Vaker blije gevoelens. Soms brede glimlach.
  1. Sanz M, Serrano J, Iniesta M, Santa Cruz I, Herrera D. Antiplaque and antigingivitis toothpastes. Monogr Oral Sci. 2013;23:27-44. doi:10.1159/000350465
  2. Harsing LG Jr, Juranyi Z, Gacsalyi I, Tapolcsanyi P, Czompa A, Matyus P. Glycine transporter type-1 and its inhibitors. Curr Med Chem. 2006;13(9):1017-1044. doi:10.2174/092986706776360932
  3. Liguori I, Russo G, Curcio F, et al. Oxidative stress, aging, and diseases. Clin Interv Aging. 2018;13:757-772. Published 2018 Apr 26. doi:10.2147/CIA.S158513
  4. Bannai M, Kawai N. New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep. J Pharmacol Sci. 2012;118(2):145-148. doi:10.1254/jphs.11r04fm
  5. Roshanzamir F, Safavi SM. The putative effects of D-Aspartic acid on blood testosterone levels: A systematic review. Int J Reprod Biomed. 2017;15(1):1-10.
  6. Socała K, Nieoczym D, Rundfeldt C, Wlaź P. Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. Pharmacol Rep. 2010;62(2):392-397. doi:10.1016/s1734-1140(10)70279-6
  7. Lee MY, Lin YR, Tu YS, Tseng YJ, Chan MH, Chen HH. Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials. J Biomed Sci. 2017;24(1):18. Published 2017 Feb 28. doi:10.1186/s12929-016-0314-8

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Sarcosine Supplement
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