- Essential role in cycle of glutathione, a powerful antioxidant produced by the body;
- Effective at treating depression;
- As effective as conventional anti-inflammatories for treating arthritis, with no unwelcome side-effects.
S-adenosyl-methionine (SAM-e) is a naturally-occuring compound in the body which promotes methylation, the process whereby methyl groups (one atom of carbon and 3 of hydrogen) are transferred from one molecule to another. Methylation is essential for many enzymatic processes and SAM-e is the most active of all methyl donors. Indeed, SAM-e has been the subject of dozens of clinical studies involving thousands of patients.
SAM-e plays a crucial role in conjunctive tissue synthesis; it eases joint pain, promotes mobility and protects cartilage from damage. In 2002, an American government agency, the Agency for Healthcare Research and Quality (AHRQ) concluded that SAM-e was 80% more effective than a placebo at relieving osteo-arthritis pain, and as effective as non-steroidal anti-inflammatories (NSAIDs) at treating osteo-arthritis. NSAIDs are associated with serious side-effects while SAM-e has health benefits for the whole body:
We introduced SAM-e into Europe in 1998 and while its price has now been reduced by over 70%, it remains an expensive nutrient. It should be recognized that:
Like SAM-e, other substances with excellent therapeutic potential are also available as nutritional supplements. Super Quercetin, for example, is a quercetin concentrate with antioxidant, anti-inflammatory, anti-carcinogenic and cardio-protective properties. Two natural extracts also recognised for their therapeutic efficacy are French oak, for reducing fatigue and improving mood, and hypericum, for combatting mild to moderate depression.
Alternative spelling/keywords : SAM e, SAMe, SAM_e, SAM
|Daily serving: 2 tablets
Number of servings per bottle: 30
|Quantity per serving|
|Elemental S-Adenosyl Methionine (obtained from 1 600 mg of S-Adenosyl L-Methionine-disulfate p-toluenesulfonate)||800 mg|
|Other ingredients: Microcrystalline cellulose, magnesium hydroxide, stearic acid, anhydrous calcium chloride, magnesium stearate, colloidal anhydrous silicon, calcium oxide, talc, shellac, arginine base, glycerol, silicon dioxide, sodium alginate.|