For centuries, certain plants have been used to promote relaxation and improve sleep naturally. Several are now the subject of scientific studies to assess their potential effects on sleep quality.
A night’s sleep generally comprises four to six cycles of around 90 minutes, although their duration may vary.
Throughout these cycles, light slow-wave sleep alternates with deep slow-wave sleep – which is more prevalent in the first part of the night – and REM sleep, which is generally more common towards the end of the night.
Deep slow-wave sleep plays a key role in physical and mental recovery, certain forms of memory consolidation, and hormonal and immune regulation (1).
Sleep that is long enough but fragmented or lacking in deep sleep can leave you feeling tired upon waking.
Difficulty falling asleep, waking up during the night and non-restorative sleep may share several underlying mechanisms.
Stress and hypervigilance can keep the arousal systems active. In chronic insomnia, this state is sometimes associated with increased activity of the stress system and cortisol secretion, although this alone does not explain night-time awakenings.
Irregular schedules, screen time, stimulants, alcohol or an unsuitable environment – such as noise, light, temperature or humidity – can also fragment sleep and impair its quality.
The bark of Magnolia officinalis, known as hou po, has long been used in traditional Chinese and Kampo medicine.
It is rich in honokiol and magnolol, two phenolic compounds currently being studied for their potential effects on relaxation mechanisms.
In mice, honokiol promoted non-rapid eye movement (NREM) sleep by modulating the benzodiazepine binding site on GABA-A receptors (2).
However, these experimental results do not allow us to conclude that magnolia increases deep sleep in humans, as the study in question was conducted solely on animals.
Another avenue of research concerns the hypothalamic-pituitary-adrenal axis, which is involved in the stress response and the secretion of cortisol (3).
In a placebo-controlled trial, 56 moderately stressed adults were given a combination of magnolia and phellodendron extracts for four weeks.
Compared with the placebo, salivary cortisol levels were 18% lower, the fatigue score was 31% lower, whilst the vigour score was 18% higher (4). However, this trial did not directly assess sleep and does not allow these results to be attributed to magnolia alone.
These results were measured in 56 moderately stressed adults (35 men and 21 women) after 4 weeks of supplementation with magnolia bark extract combined with phellodendron extract (500 mg per day), compared with a placebo (4).
Discover Deep Sleep Complex, a formula designed to support continuous, restorative sleep, containing 200 mg of Magnolia officinalis bark extract standardised to 90% honokiol and magnolol per daily dose.
Traditionally used in Europe, valerian root is employed to relieve mild symptoms of nervous tension and promote sleep.
Valerenic acid, one of its most extensively studied compounds, may modulate GABA-A receptors via a site distinct from the benzodiazepine binding site explored for honokiol (5).
However, reviews remain cautious: trials use heterogeneous extracts and mainly suggest a possible improvement in the subjective quality of sleep. Results regarding sleep onset latency and sleep architecture remain variable.
Discover Natural Sleep Formula, Advanced Sleep Formula two formulations combining valerian with other active ingredients designed to promote sleep.
Native to the Americas, passionflower is traditionally used to relieve mild symptoms of mental stress and promote sleep.
It contains flavonoids, including vitexin. Preclinical studies suggest that certain extracts may modulate GABAergic transmission, but the compounds responsible and their precise mechanisms remain poorly understood.
Its main benefit here lies in the relaxation it can promote when nervous tension and ruminating thoughts delay falling asleep.
Discover Advanced Sleep Formula which contain passionflower, as well as Natural Sleep Formula, based on a different combination of plants.
Recognisable by its lemon-scented leaves, lemon balm is traditionally used to relieve mild symptoms of stress and promote sleep.
Rosmarinic acid, one of its main phenolic compounds, has been shown in vitro to inhibit GABA transaminase, an enzyme involved in the breakdown of GABA (6). This potential mechanism therefore appears to affect the availability of this neurotransmitter rather than acting directly on its receptors.
Lemon balm is also traditionally associated with digestive comfort, which sets it apart from the other plants featured here when bloating or indigestion disrupts sleep.
Discover Muscle Relaxing Formula, a relaxation-focused formula that contains lemon balm, amongst other ingredients.
Green tea can be stimulating due to its caffeine content. L-theanine, isolated from its leaves, has a different profile: this amino acid is being studied for its ability to promote a state of relaxation without significant sedation.
In particular, it may increase the activity of alpha brain waves, which are associated with a relaxed yet alert state. This profile sets it apart from the plants mentioned earlier: L-theanine is primarily studied for its potential effect on hyperarousal and sleep quality.
In a 2019 randomised trial, taking 200 mg per day for four weeks improved certain components of the PSQI questionnaire, particularly those relating to sleep latency and sleep disturbances (7).
Discover Deep Sleep Complex, which provides 200 mg of L-theanine per daily dose, alongside, amongst other ingredients, magnolia extract.
Difficulty falling asleep and waking up during the night are not always caused by the same factors: formulations combining several active ingredients, each studied for distinct mechanisms of action, can therefore offer a complementary approach.
Among the non-plant-based compounds is L-ornithine, an amino acid involved in the urea cycle, which takes place mainly in the liver.
In a 2014 trial, taking 400 mg of L-ornithine daily for 8 weeks in 52 people was associated with a reduction in serum cortisol and the cortisol/DHEA-S ratio, as well as an improvement in perceived sleep quality (8).
PeptiSleep™, meanwhile, is a brown rice protein hydrolysate containing bioactive peptides identified using artificial intelligence. It is currently undergoing clinical trials focusing on sleep quality, duration and continuity.
Combined with magnolia and L-theanine, these compounds form the basis of a formula that targets several mechanisms potentially involved in stress, hyperarousal and sleep regulation.
Discover Deep Sleep Complex, which combines four complementary active ingredients: PeptiSleep™, L-ornithine, Magnolia officinalis extract and L-theanine.
Herbs can be helpful as part of a holistic approach to sleep.
However, they are no substitute for a healthy lifestyle or appropriate medical care: if your sleep problems persist or are affecting your daily life, consult a healthcare professional.
Habits to adopt include:
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