0
en
US
WSMUS
65416828
There are no items in your cart.
Menu

How could L-tryptophan affect sleep?

2026-01-21

L-tryptophan is an amino acid involved in various biological mechanisms, some of which are linked to sleep. Scientific research has looked into its involvement in these processes.

Find out whether L-tryptophan has any effect on sleep

What is L-tryptophan?

L-tryptophan is an essential amino acid. The human body cannot manufacture it, but needs it to carry out certain biological functions.

In particular, it is involved in protein synthesis and in the production of molecules involved in various physiological processes.

More specifically, the body uses it as a precursor for serotonin and melatonin. These two neurotransmitters are mainly involved in mechanisms linked to mood and the regulation of the sleep-wake cycle (1).

However, the exact influence of L-tryptophan on sleep depends on numerous metabolic steps, and its effect cannot be considered direct.

This amino acid is found in a variety of foods, often of animal origin, but sometimes also of plant origin. Common food sources include:

  • dairy products
  • red and white meat
  • eggs
  • legumes, including soya
  • nuts

It can also be found as a dietary supplement, in tablet or capsule form.

-Discover the L-Tryptophan dietary supplement designed to increase your intake of this amino acid.

From L-tryptophan to melatonin: what you need to understand

Once present in the body, L-tryptophan is first converted into 5-HTP, then into serotonin and finally into melatonin (2).

Melatonin is a hormone naturally produced by the pineal gland that helps regulate sleep. It is also commonly referred to as the sleep hormone.

In particular, melatonin helps to reduce the time it takes to fall asleep and alleviate the subjective feelings associated with jet lag (3).

This is why it is sometimes recommended as a supplement to promote better sleep.

However, it is only effective in the case of sleep problems linked to a lack of melatonin, but not if they are linked to another problem (environment not conducive to falling asleep, underlying pathology, anxiety, etc.).

This process therefore suggests the existence of an indirect link between the presence of L-tryptophan in our bodies and the regulation of sleep-related mechanisms.

-Discover Natural Sleep Formula, a natural sleep supplement rich in plant extracts and enriched with tryptophan.

Practical tips and ingredients for better sleep

The right habits to adopt for better sleep

Improving the quality of your sleep depends above all on a lifestyle that respects your biological rhythms.

A few simple habits can help you fall asleep more easily and stay asleep throughout the night.

To begin with, it's essential to:

  • go to bed and get up at regular times to get your body used to a certain routine
  • keep your bedroom dark, calm and cool, to limit any outside disturbance
  • avoid heavy meals in the evening and stimulants at the end of the day, as they disrupt sleep
  • engage in regular physical activity, preferably during the day, to tire the body and increase the ‘sleep drive’ by the evening

In addition to these good habits, it is worth limiting exposure to intense artificial lighting and screens in the evening, as these are sources of blue light.

This type of light deceives the brain, which tends to confuse it with daylight, and so it doesn't trigger the secretion of melatonin early enough to help you fall asleep.

Furthermore, if you're naturally anxious, it's also a good idea to use stress management and relaxation techniques such as yoga, meditation or deep breathing exercises to calm you down at the end of the day.

Targeted ingredients for a natural boost

Certain ingredients are being studied for their potential to help you relax or improve the quality of your sleep.

Of course, melatonin figures prominently among them. It can be particularly useful for people who have difficulty falling asleep during specific periods, such as a change in routine or jet lag.

Melatonin can be taken occasionally to speed up the process of falling asleep or reduce jet lag.

-Discover Melatonin, a dietary supplement packaged in tablet form for rapid action (30 to 60 minutes after taking).

When sleep is disrupted by factors other than a simple lack of melatonin (stress, fast pace of life, anxiety), a more complete formula may be of interest.

It can incorporate different ingredients studied for their role in relaxation or in balancing the sleep-wake cycle.

Valerian, for example, helps maintain natural sleep patterns. It has been studied for its effects on reducing psychomotor agitation and the time it takes to fall asleep (4).

For its part, passionflower (Passiflora incarnata) promotes a healthy night's rest and is thought to have a potential impact on the GABA system, helping to calm the nerves (5).

-Discover the Advanced Sleep Formula food supplement, which contains melatonin, as well as vitamin B6, which helps reduce fatigue, and plant extracts studied for their action on sleep, such as valerian and passionflower.

Today, gummies are an interesting option that is easy to integrate into your daily routine, allowing you to test the effects of natural ingredients on your sleep, such as cannabidiol (CBD).

CBD is a phytocannabinoid molecule found in hemp, the effects of which are being studied in the context of relaxation and sleep management (6-8).

-Discover the Sleep Gummies dietary supplement, a chewable gummy formula containing CBD, melatonin and plant extracts traditionally known for their sleep-inducing effects.

SUPERSMART ADVICE

References

  1. Richard DM, Dawes MA, Mathias CW, Acheson A, Hill-Kapturczak N, Dougherty DM. L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications. Int J Tryptophan Res. 2009 Mar 23;2:45-60. doi: 10.4137/ijtr.s2129. PMID: 20651948; PMCID: PMC2908021.
  2. Peuhkuri K, Sihvola N, Korpela R. Dietary factors and fluctuating levels of melatonin. Food Nutr Res. 2012;56. doi: 10.3402/fnr.v56i0.17252. Epub 2012 Jul 20. PMID: 22826693; PMCID: PMC3402070.
  3. Cardinali DP, Brusco LI, Pérez Lloret S, Furio AM. Melatonin in sleep disorders and jet-lag. Neuro Endocrinol Lett. 2002 Apr;23 Suppl 1:9-13. PMID: 12019344.
  4. Yuan CS, Mehendale S, Xiao Y, Aung HH, Xie JT, Ang-Lee MK. The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity. Anesth Analg. 2004 Feb;98(2):353-358. doi: 10.1213/01.ANE.0000096189.70405.A5. PMID: 14742369.
  5. Guerrero FA, Medina GM. Effect of a medicinal plant (Passiflora incarnata L) on sleep. Sleep Sci. 2017 Jul-Sep;10(3):96-100. doi: 10.5935/1984-0063.20170018. PMID: 29410738; PMCID: PMC5699852.
  6. Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18-041. doi: 10.7812/TPP/18-041. PMID: 30624194; PMCID: PMC6326553.
  7. Ranum RM, Whipple MO, Croghan I, Bauer B, Toussaint LL, Vincent A. Use of Cannabidiol in the Management of Insomnia: A Systematic Review. Cannabis Cannabinoid Res. 2023 Apr;8(2):213-229. doi: 10.1089/can.2022.0122. Epub 2022 Sep 23. PMID: 36149724.
  8. Lavender I, Garden G, Grunstein RR, Yee BJ, Hoyos CM. Using Cannabis and CBD to Sleep: An Updated Review. Curr Psychiatry Rep. 2024 Dec;26(12):712-727. doi: 10.1007/s11920-024-01564-7. Epub 2024 Nov 29. Erratum in: Curr Psychiatry Rep. 2024 Dec;26(12):728. doi: 10.1007/s11920-024-01580-7. PMID: 39612156.
  9. Dec;26(12):712-727. doi: 10.1007/s11920-024-01564-7. Epub 2024 Nov 29. Erratum in: Curr Psychiatry Rep. 2024 Dec;26(12):728. doi: 10.1007/s11920-024-01580-7. PMID: 39612156.

Share

Comments

You must be connected to your account to leave a comment

Be the first to review this article

Secure Payment
34 Years of Experience
Returns
Fast Shipping
FREE delivery on orders over $25