Alpha lipoic acid is unique in neutralizing around six types of particularly damaging free radicals. It's also a chelator of several toxic metals. It's used preventatively and therapeutically in a number of diseases, in particular, the complications of diabetes.
What are the benefits associated with Alpha Lipoic Acid?
Alpha Lipoic Acid is called the universal antioxidant because:
It's active in aqueous and lipid regions (it's both water-soluble and fat-soluble).
It recycles vitamin C, vitamin E, Coenzyme Q10 and Glutathione after their use by the body and therefore significantly increases their effectiveness.
It is rapidly converted to its metabolite dihydrolipoic acid in most tissues and in this form, protects against free radicals.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Composition
Daily serving: 2 tablets
Number of servings per bottle: 30
Quantity
per serving
Alpha lipoic acid
500 mg
Other ingredients: Acacia gum, rice bran.
Each vegetarian capsule contains 250 mg of alpha-lipoic acid.
Directions for use
Take one or two capsules a day. Therapists often recommend 3-6 capsules a day.
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Matthew2021-12-22
I read this helps nerves in the body. I'm giving it a try.
References
Carreau JP. Biosynthesis of lipoic acid via unsaturated fatty acids. Methods Enzymol. 1979;62:152-8.
Packer L, Witt H, Trischler HJ. Alpha-Lipoic acid as a biological antioxidant. Freed Radic. Biol. Med., 1995, 19, 227-250.
Reed, LJ. A trail of research from lipoic acid to alpha-keto acid dehydrogenase complexes. J Biol. Chem., 2001, 276, 38329-38336
Singh and Jialal, Alpha-lipoic acid supplementation and diabetes. Nutr Rev. 2008 Nov;66(11):646-57. doi: 10.1111/j.1753-4887.2008.00118.x.
Chng HT, New LS, Neo AH, Goh CW, Browne ER, Chan EC. Distribution study of orally administered lipoic acid in rat brain tissues. Brain Res. 2009 Jan 28;1251:80-6. doi: 10.1016/j.brainres.2008.11.025. Epub 2008 Nov 19.
Breithaupt-Grogler, Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data. Eur J Pharm Sci. 1999 Apr;8(1):57-65.
Goraca, Huk-Kolega et al. Lipoic acid - biological activity and therapeutic potential. Pharmacol Rep. 2011;63(4):849-58.
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