A study reveals the effects of magnesium L-threonate on sleep

Magnesium L-threonate: a unique form that crosses the blood-brain barrier

Magnesium is an essential mineral salt, involved in over 300 chemical reactions in the body.

In particular, it helps to:

• reduce fatigue
• support normal energy metabolism
• support normal functioning of the nervous system
• support psychological function

But not all forms of magnesium are created equal: for example, L-threonate, an innovative, patented compound, offers specific benefits.

Derived from the magnesium salt of L-threonic acid, this form of magnesium stands out for its exceptional ability to cross the blood-brain barrier, a biological boundary that separates the bloodstream from brain tissue (it protects the brain by limiting the entry of potentially toxic molecules).

This unique characteristic enables it to act directly in the brain, where other forms of magnesium cannot easily penetrate.

Several studies suggest that magnesium L-threonate could support cognitive functions such as memory, concentration and neuronal plasticity (1-2).

And a recent study reveals that it could also have effects on the quality of rest and the regulation of the sleep-wake cycle (3).

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Magnesium L-threonate and sleep: what does the study tell us?

In 2024, a randomised, double-blind study was carried out on 80 adults aged between 35 and 55, to assess the effects of magnesium L-threonate in people suffering from persistent sleep disorders.

Participants received either a placebo or a daily supplement of L-threonate magnesium (1 g/day of MgT) for 3 weeks.

The results suggest several interesting effects:

• improved sleep quality: magnesium L-threonate supplementation appears to have improved the score for deep sleep (stage N3) and REM sleep, two phases essential for recovery
• improved daytime well-being: participants who received the supplement reported a better mood, more stable energy, increased vigilance and improved productivity during the day

Although they remain to be confirmed by longer studies involving larger populations, these results highlight the potential of magnesium L-threonate in the natural treatment of sleep disorders.

They should also be viewed in the context of a holistic approach where lifestyle, stress management and medical support remain essential for promoting quality sleep.

What are the natural solutions for better sleep?

Although magnesium L-threonate is showing promising results, it is important to remember that recurrent sleep disturbance requires medical advice.

Underlying pathologies or drug treatments can sometimes be to blame, so it's important to diagnose them so that they can be treated.

Adopting good habits on a daily basis

Simple lifestyle adjustments can help to improve sleep quality (4):

• stick to a regular timetable: going to bed and getting up at set times can help stabilise your biological clock and encourage you to fall asleep more quickly
• limit the use of screens before bedtime: the blue light emitted by screens can disrupt the production of melatonin, the hormone that signals to the body that it's time to sleep
• avoid caffeine at the end of the day: coffee, tea, soft drinks or chocolate can delay sleep onset and reduce sleep quality
• take care with the bedroom environment: a calm, dark and well-ventilated atmosphere helps to create an environment conducive to deep, restorative rest

Opt for magnesium-based supplements

Food supplements can be a useful natural aid, but should be used with discretion and always in consultation with a health professional.

Magnesium remains one of the most studied nutrients for supporting the nervous system and reducing fatigue (5-6).

Discover the Magnesium L-Threonate supplement, an innovative solution for supporting normal nervous and psychological functions.

Other forms of magnesium may also be of interest, particularly when combined for synergistic action.

Discover OptiMag, a unique, synergistic combination of 8 exceptional forms of magnesium, highly bioavailable and particularly well tolerated by the intestines.

What other supplements can help you sleep better?

Certain plants are also known for their potential benefits for sleep:

• lemon balm contributes to optimal relaxation and normal sleep
• valerian is traditionally used to help promote sleep onset and natural sleep
• hops are used for their soothing and relaxing effects, contributing to normal sleep

Discover Natural Sleep Formula, a natural food supplement rich in plant extracts, to help you fall asleep and return to normal sleep.

Melatonin is a hormone naturally produced by the body, which helps reduce the time it takes to fall asleep (7).

Discover Melatonin 1 mg, a simple formula that helps reduce the time it takes to fall asleep, packaged in tablet form.

There are also combined formulas that combine melatonin and plant extracts, for an overall effect on falling asleep and sleep.

Discover Advanced Sleep Formula, a complete formula combining melatonin, relaxing plant extracts and vitamin B6 to help you fall asleep.

And for those who prefer something fun and tasty, there are also gummies enriched with melatonin and plant extracts.

Discover Sleep Gummies, a gentle, sugar-free formula containing CBD to help you fall asleep.

Finally, chronic stress is one of the great enemies of sleep (8). Reducing nervous tension and stress can help you get a better night's rest.

Discover Stress Relief Formula, a synergy of natural active ingredients to help you better manage the effects of everyday stress.