![Nattokinase is formulated from nattokinase enzyme, from the famous traditional Japanese food natto. Soybeans used to make natto]()
Nattokinase Supplement – Natto Enzyme to Improve Heart Health & Circulation
Nattokinase supplement is formulated from a very specific enzyme called nattokinase, identified in the famous traditional Japanese food natto, made from soybeans fermented with the bacteria Bacillus subtilis or Bacillus natto.
What is Natto?
Consumed therapeutically for centuries, natto first became known for its high content in vitamin K2. Involved in coagulation of the blood, cardiovascular health, and bone metabolism, this vitamin has been extracted from natto for several years for formulation into supplements. More recently, scientists have highlighted the benefits of an enzyme found in natto called nattokinase.
Despite its health benefits, this fermented food is relatively unpopular outside Asia because of its slimy appearance, ammonia-like smell and strong taste. To get around these disadvantages and make natto's benefits available, dietary supplements have been developed from some of the active principles in this fermented food. This is the case with our nattokinase-based supplement, isolated from natto for its cardiovascular health benefits.
What are the Benefits Associated with Nattokinase?
Widely-studied in recent years, nattokinase has demonstrated powerful fibrinolytic activity – the ability to regulate and prevent the formation of blood clots (thrombi). This is a significant benefit given that clots in the vascular system can lead to serious complications.
As a result of its fibrinolytic activity, nattokinase is able to dissolve clots in the bloodstream and prevent the formation of new obstructions. It thus helps prevent atherosclerosis, which is characterized by the formation of atheromatous plaques due to the accumulation of fat on artery walls. As they develop, these plaques can cause a thrombosis – a partial or total obstruction of the arteries. Ultimately, this can lead to serious consequences such as a heart attack or stroke. By thinning the blood, nattokinase reduces cardiovascular complications. It also helps combat hypertension.
The benefits of this enzyme are now available as a nutritional supplement. This is delivered in softgels, each containing 50 mg nattokinase, with a suggested dose of between 2 and 4 capsules a day, depending on individual needs and the advice of your therapist.
Alongside nattokinase, other cardio-protective effects are available in supplement form from the SuperSmart catalogue such as the protective benefits of and the efficacy of for strengthening artery walls.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Composition
Daily serving: 4 softgels
Number of servings per bottle: 15 |
Quantity per serving |
Nattokinase |
200 mg |
D-Alpha-Tocopherol |
40 mg* |
Other ingredients: soy lecithin, white rice bran oil, beeswax.
*RDA in D-Alpha-Tocopherol: 333%. |
Warning: contains soy.
Directions for use
Adults: Take 2 to 4 softgels a day, or as advised by your therapist.
Each softgel contains 50 mg of nattokinase corresponding to 650 FU (fibrinolytic activity units).
Precautions: do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used as a substitute for a varied, balanced diet or a healthy lifestyle. Keep out of children’s reach. Store away from light, heat, and humidity. As with any nutritional supplement, consult a health care practitioner before use if you are pregnant, breastfeeding, or have a medical condition.
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References
- Chen H, McGowan EM, Ren N, et al. Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases. Biomark Insights. 2018;13:1177271918785130. Published 2018 Jul 5. doi:10.1177/1177271918785130
- Susen, S., Zawadzki, C., Asseman, P., & Jude, B. (2006). Traitements fibrinolytiques. EMC - Hématologie, 1(1), 1–8. doi:10.1016/s1155-1984(03)000
- Nagata C, Wada K, Tamura T, et al. Dietary soy and natto intake and cardiovascular disease mortality in Japanese adults: the Takayama study. Am J Clin Nutr. 2017;105:426–431.
- Sumi H, Hamada H, Tsushima H, Mihara H, Muraki H. A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet. 1987;43:1110–1111.
- Urano T, Ihara H, Umemura K, et al. The profibrinolytic enzyme subtilisin NAT purified from Bacillus subtilis cleaves and inactivates plasminogen activator inhibitor type 1. J Biol Chem. 2001;276:24690–24696.
- Fujita M, Hong K, Ito Y, Fujii R, Kariya K, Nishimuro S. Thrombolytic effect of nattokinase on a chemically induced thrombosis model in rat. Biol Pharm Bull. 1995;18:1387–1391.
- Fu Y-S, Li Y-L, Zhang Y. Toxicological safety assessment on safety of nattokinase capsule. Prac Prev Med. 2012;19:1714–1716.