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SAM-e 400 mg

SAM-e Supplement (S-Adenosyl-Methionine) to Help Support Mood and Emotional Well-Being *

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S-adenosyl-methionine (SAM-e) is a naturally occurring compound that acts as one of the body’s most active methyl donors.

  • May help support the liver’s natural synthesis of glutathione, a key antioxidant.*
  • Has been studied for its potential role in supporting mood balance and emotional well-being.*
  • May contribute to joint comfort, mobility, and overall cartilage health.*

$99.00

60 tablets

One-time purchase

$99.00

$91.08

60 tablets

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SAM-e 400 mg

Vegan
Gluten-Free
No Controversial Excipients
Lactose-Free
No Sweeteners
No Added Sugars
  • Product Details
  • Supplement Facts
  • Suggested Use

S-adenosyl-methionine (SAM-e) is a naturally occurring compound in the body that plays a central role in methylation, the process of transferring methyl groups between molecules. Methylation is essential for numerous enzymatic reactions, and SAM-e is considered one of the body’s most active methyl donors. It has been the focus of many studies exploring its potential applications in health and wellness.*

What Are the Potential Benefits Associated with SAM-e?

SAM-e is involved in connective tissue synthesis and may help support joint comfort, mobility, and cartilage health.* It has also been investigated for its role in supporting emotional well-being and healthy liver function.*

  • Supports the liver’s natural synthesis of glutathione: glutathione is a key antioxidant involved in detoxification and cellular protection.*
  • Studied for mood support: SAM-e has been researched for its possible role in promoting mood balance and emotional well-being.*
  • Plays a role in energy metabolism: SAM-e participates in methylation pathways that may contribute to energy production and DNA stability.*
  • May support brain health: animal and preliminary studies suggest SAM-e could influence antioxidant status and help maintain normal cognitive function as part of healthy aging.*

Why Choose SAM-e 400 mg?

SAM-e remains a premium nutrient due to its complex structure and stability. Our formulation is designed to provide both high quality and reliable bioavailability.*

  • Contains a high proportion of the active form (S,S): this is the biologically active isomer naturally used by the body.*
  • Stability and protection: SAM-e is a delicate compound that requires careful handling. Our tablets are double foil blister-packed and enteric-coated to help preserve activity and protect against gastric acidity.*
  • Produced naturally: obtained through microbiological fermentation, without the use of chemical solvents, and packaged to maintain potency.*

Like SAM-e, other antioxidants and plant extracts are also available at SuperSmart. Super Quercetin offers concentrated flavonoids with antioxidant potential, French Oak extract has been studied for its possible role in reducing fatigue, and St John’s Wort has long been used to help support mood balance.*

WARNINGS

Do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used as a substitute for a varied and balanced diet or a healthy lifestyle.

STORAGE

Store in a cool, dry place away from direct sunlight, heat, and humidity. Keep out of reach of children.

PREGNANCY AND MEDICAL CONDITIONS

If you are pregnant, breastfeeding, or have any medical conditions, consult your healthcare provider before using this product.

SUPPLEMENT INTERACTIONS

Consult your healthcare provider before use, especially if you are taking any medications or other supplements as there may be potential interactions.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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