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Dietary supplement of ursolic acid
Dietary supplement of ursolic acid
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Ursolic Acid
Sports and exercise
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Our ursolic acid supplement is extracted from the leaves of the Japanese loquat tree:

  • May help maintain muscle mass in individuals following low-calorie diets.
  • Protects the skin from photo-aging and is a potent inhibitor of elastase.
  • Has significant anti-inflammatory and antioxidant properties.
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Rosemary leaves rich in ursolic acid

Ursolic Acid Supplement Extracted from Rosemary Leaves

Supersmart’s ursolic acid supplement comes in vegetarian capsules and provides significant benefits for your overall well-being. In studies, it has demonstrated anti-inflammatory and antioxidant properties and shown to inhibit some viruses. The leaves of the Japanese loquat tree (Eriobotrya japonica) contain valuable substances known as oleanolic acid, amygdalin, and ursolic acid. They also contain pentacyclic triterpene.

There are only a few foods high in ursolic acid, including fruit skins, such as apples and grapes, as well as common herbs, such as rosemary, thyme, oregano, and sage. While eating ursolic acid foods is a good way to increase intake naturally, it can be difficult to consume enough of those foods to meet your daily requirement. That makes supplements one of the best sources of ursolic acid.

Ursolic acid and its isomer, oleanolic acid, are chemically almost identical. Their structure only differs in the position within the methyl group (CH3). However, both offer potentially vital health benefits.

So, what is ursolic acid used for? In nature, ursolic acid is found in a variety of plants, but you can also take ursolic acid capsules to ensure proper intake. So far, the science regarding ursolic acid health benefits is largely preliminary, but studies continue to exhibit potential advantages. One study indicates that there may be ursolic acid skin benefits, while another study indicates an increase in skeletal muscle growth.

While we don't have all of the evidence needed yet, it's clear that people take ursolic acid supplements to promote their overall well-being.

Ursolic Acid Benefits

Ursolic acid has traditionally been used for the skin as it appears to repair damaged tissue in the cutaneous barrier and scalp. Taking ursolic acid for skin care may also protect against photo-aging and could be a potent inhibitor of elastase, an enzyme present in the skin which attacks structural proteins.

With its multitude of properties, ursolic acid is an important addition to the range of phytoceutical resources available for anti-aging in general.

Because ursolic acid has also shown to have anti-infection effects and inhibits some viruses, it is used to promote overall health. Recent studies on rats have even indicated that its inhibitory power (reversible) on human leukocyte elastase may have potential in combating inflammatory lung infections, such as the H1N1 and SARS viruses. Ursolic acid also has shown anti-microbial and immune-stimulant effects, specifically against the effects of tuberculosis, according to one study.

Other research shows it may inhibit memory impairment by inhibiting the enzyme acetylcholinesterase — reducing the enzymatic degradation of acetylcholine and improving cholinergic transmission.

What do studies show about ursolic acid supplements?

Benefits for Muscle Growth

Studies show ursolic acid may be beneficial to the body’s muscles. Potential benefits of ursolic acid for muscles include:

  • Ursolic acid may help stem sarcopenia (muscle loss associated with aging and certain diseases).
  • Animal studies have demonstrated its potential to increase muscle volume and power.
  • According to researchers, ursolic acid may support efforts to reduce body fat, fasting blood glucose, and triglyceride levels by acting on two key hormones: IGF-1 and insulin.
  • Taking ursolic acid for bodybuilding is one of its most popular uses in America.
  • By regulating certain RNA messengers, taking ursolic acid for muscle may benefit individuals following low-calorie diets.

Antioxidant and Anti-inflammatory Properties

Ursolic acid has been studied to be a powerful and natural anti-inflammatory that inhibits human leukocyte elastase (HLE) as well as 5-lipoxygenase and cyclooxygenase-2 activity and prostaglandin synthesis. Other potential ursolic acid supplement benefits are its antioxidant and anti-MMP-9 (matrix metalloproteinase-9) effects.

Those wishing to achieve a more sculpted figure may be interested in other supplements available to buy at Supersmart, such as Crominex® 3+ for muscle mass/fat mass ratio. For muscle weakness, molecules with anti-aging effects, like Nicotinamide Mononucleotide are available as nutritional supplements.

Buy Ursolic acid to improve overall muscle health and possibly increase anti-inflammatory protection.

Daily dose : 6 capsules
Number of doses per pack: 15
Amount per dose
Ursolic acid (from 1200 mg of Rosemary leaves standardized to 25% ursolic acid) 300 mg
Other ingredients: Acacia gum, rice flour.
Directions for use

How To Take Ursolic Acid Capsules

Even with the best ursolic acid supplements, it’s important to follow the instructions on the label. To receive the maximum health benefits of ursolic acid, we recommend taking three to six vegetarian capsules, totaling 300 mg of ursolic acid, daily. We recommend taking the capsules throughout the day, rather than taking all six capsules at once. Supersmart’s ursolic acid supplements should be stored away from direct light, heat, and humidity.

4.5 /5 2 reviews
4.0 / 5
4.5 / 5
Value for money
4.5 / 5

Reviews 2
50 %

I have MS & read reports on Ursolic Acid being studied for improving some MS symptoms.
So far any results are minor or questionable.
.I have noted the following: For the past several years I have ben experiencing some small, hard, & rough growths on my head & ears. After 2 weeks of taking 3 to 6 capsules / day I noted these growths were disappearing. After 2 months of use I have none of these growths.
I have not changed anything else in my diet & am not on any prescription drugs.

  1. Bahrami SA, Bakhtiari N. Ursolic acid regulates aging process through enhancing of metabolic sensor proteins level. Biomed Pharmacother. 2016;82:8-14. doi:10.1016/j.biopha.2016.04.047
  2. Kunkel SD, Elmore CJ, Bongers KS, et al. Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease. PLoS One. 2012;7(6):e39332. doi:10.1371/journal.pone.0039332
  3. Ying QL, Rinehart AR, Simon SR, Cheronis JC. Inhibition of human leucocyte elastase by ursolic acid. Evidence for a binding site for pentacyclic triterpenes. Biochem J. 1991;277 ( Pt 2)(Pt 2):521-526. doi:10.1042/bj2770521
  4. Zerin T, Lee M, Jang WS, Nam KW, Song HY. Anti-inflammatory potential of ursolic acid in Mycobacterium tuberculosis-sensitized and concanavalin A-stimulated cells. Mol Med Rep. 2016;13(3):2736-2744. doi:10.3892/mmr.2016.4840
  5. Liang W, Zhao X, Feng J, Song F, Pan Y. Ursolic acid attenuates beta-amyloid-induced memory impairment in mice [published correction appears in Arq Neuropsiquiatr. 2017 Jan;75(1):i]. Arq Neuropsiquiatr. 2016;74(6):482-488. doi:10.1590/0004-282X20160065
  6. Kunkel SD, Elmore CJ, Bongers KS, et al. Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease. PLoS One. 2012;7(6):e39332. doi:10.1371/journal.pone.0039332
  7. Checker R, Sandur SK, Sharma D, et al. Potent anti-inflammatory activity of ursolic acid, a triterpenoid antioxidant, is mediated through suppression of NF-κB, AP-1 and NF-AT. PLoS One. 2012;7(2):e31318. doi:10.1371/journal.pone.0031318

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