Your cart is empty

Out of stock

Plasminogen Activator

Plasmin Supplement for Healthy Blood Vessels

No reviewsRead reviews

The best natural compounds for cardiovascular health and longevity.

  • Helps unclog the arteries by preventing new plaque from forming and reducing existing deposits.
  • High in nattokinase and d-alpha tocopherol which activate the plasminogen responsible for eliminating blood clots.
  • Contains serrapeptase which helps break down dead cells and the accumulation of damaged tissue.
  • Supports healthy blood flow.
  • Contains high levels of powerful antioxidants (phosphorylated ascorbate, pterostilbene, OPCs...) which help fight cellular aging.

Buy now

60 Caps.



60 Caps.

This product is not available for auto-delivery

Plasminogen Activator

No controversial excipients
No sweeteners

Plasminogen Activator is a superior quality dietary supplement which combines the best natural substances for supporting good cardiovascular health and longevity.

Its carefully-selected compounds help prevent the formation of arterial plaque and reduce existing plaque. Certain of its ingredients, such as nattokinase and d-alpha tocopherol, are even able to directly activate plasminogen, the precursor of plasmin. Plasmin helps break down the fibrin that goes on to form blood clots (1-3). This new formulation has also been developed to promote optimal blood flow.

Plasminogen Activator also contains powerful antioxidant compounds which help protect the body from the harmful effects of oxidative stress, a key factor in cardiovascular problems and aging (4-5).

What Exactly is in Plasminogen Activator?

The exceptional Plasminogen Activator contains 6 bioactive ingredients carefully-chosen to act in synergy to protect your arteries:

  • Nattokinase – this is an enzyme extracted from natto, a Japanese food made of fermented soybeans. By activating plasminogen, nattokinase helps break down fibrin, a substance that circulates in the blood and can build up to the point where it causes a blood clot to form. In addition, nattokinase helps reduce the activity of renin, a compound that increases blood pressure. Nattokinase thus helps both to prevent the formation of clots and reduce hypertension. It also has anti-atherosclerotic properties (6-7).
  • Serrapeptase – this enzyme, able to break down certain proteins, is used by silkworms to dissolve their cocoons. In the human body, serrapeptase breaks down dead or damaged tissue. It thus helps dissolve plaque, the harmful fibrous layer that builds up on artery walls, and clots, without affecting healthy cells. It also promotes a reduction in swelling by draining fluid that accumulates in tissues (8-10).
  • Grape seed extract standardized to 95% oligoproanthocyanidins (OPCs) – OPCs are flavonoid polyphenols and particularly effective antioxidants. A number of studies show that OPCs also help maintain the endothelium (the layer of cells lining the interior surface of blood vessels and thus in direct contact with circulating blood) (11-12).
  • Pterostilbene – found in grapes and blueberries, this super antioxidant is similar to resveratrol but is even more bioavailable. Pterostilbene helps both prevent the accumulation of LDL cholesterol and normalize blood pressure. It also has soothing and stress-relieving effects, a significant benefit given that stress is a major factor in the deterioration of arteries and veins (13-14).
  • Magnesium ascorbyl phosphate – this rare and stable form of vitamin C is 20 times more powerful than standard forms of vitamin C. It helps combat oxidative stress and support collagen production, which plays a role in healthy blood vessel function (15-16).
  • Vitamin E, in the form of d-alpha tocopherol succinate – several studies suggest that this natural form of vitamin E activates plasminogen and has a role in cleansing atheromatous deposits from arteries, thus preventing them from narrowing. Vitamin E is also an excellent antioxidant (17-19).

What Beneficial Effects does Plasminogen Activator have on the Arteries?

First, nattokinase, serrapeptase, pterostilbene, and d-alpha tocopherol help prevent and eliminate the atheromatous plaque which progressively clogs up the arteries (20-23). In addition, nattokinase and serrapeptase exert a powerful 'fibrinolytic' effect: they play a part in preventing the formation of blood clots or 'thrombi' (24-25).

Plasminogen Activator's dual action helps reduce the risk of arterial obstruction which can cause serious cardiovascular problems such as myocardial infarction (heart attack), stroke, angina, and sudden ischemia.

By helping to cleanse the arteries, serrapeptase and d-alpha tocopherol also have a blood-thinning effect (26-27). And nattokinase and pterostilbene help lower blood pressure and reduce hypertension (28-29).

Lastly, as potent antioxidants, ascorbyl magnesium phosphate, OPCs, pterostilbene, and vitamin E combat oxidative stress. Several studies have shown that free radical attack on cells is greatly implicated in the development of cardiovascular disease and aging in general (30-32).

3 Additional Benefits of this Heart-Healthy, Anti-Aging Formulation

In addition to these principal benefits:

  • The ascorbyl magnesium phosphate in Plasminogen Activator also supports a robust immunity (33).
  • The nattokinase and serrapeptase may also be able to dissolve amyloid plaques (which can form in the brain and impair cognitive functions) (34).
  • And, according to one study, pterostilbene may help regulate blood sugar levels (35).

Plasmin Capsules' Potential Side Effects

For the vast majority of people, taking this antioxidant supplement is perfectly safe. This plasminogen activator is designed to provide a range of health benefits. However, it is always important to do your own research into the side effects of any supplement you take, and plasmin supplements are no exception.

There is plenty of material online on supplements to unclog arteries and further information on plasminogen function. You can gain access to various research materials, including scientific studies and anecdotal evidence from others who have already added the plasminogen activator supplement to their diets.

If you already take prescription medication, you should speak to your doctor about plasminogen activator function. They will be able to go through your medical history and analyze any medications you might be taking. Adverse drug interactions are rare, but they can happen not only with a plasmin capsule but with any supplement. It is always best to be safe.

Furthermore, if adding plasmin supplements to your diet, make sure you monitor yourself for any plasminogen activator side effects. In the event you experience any unpleasant or uncomfortable side effects, stop taking the plasminogen supplement immediately and speak to your doctor.

Blocked Arteries: Other Natural Ways of Lowering your Risk

There are several additional steps you can take to prevent the development of atheromatous plaque. We know these atheromas are likely to obstruct arteries over time (a process called 'stenosis') but they can also become suddenly detached, causing a blood clot, which can itself block the artery, known as 'thrombosis'. To reduce the risk of such cardiac problems, you can try to:

  • Stop smoking;
  • Take regular exercise;
  • Avoid stress whenever possible;
  • Eat a balanced diet (with plenty of fruit and vegetables, as well as minimal salt and fat);
  • Reduce your alcohol intake;
  • Control your hypertension and monitor your cholesterol.

Supplements to take in Tandem with Plasminogen Activator

If you are interested in taking other supplements to support your cardiovascular system and circulation, Plasminogen Activator can be combined with a course of Arctic Plankton Oil. This nutritional gem, consisting of a zooplankton-sourced oil, is excellent for the heart. Its high omega-3 content, in particular, will help reduce hypertension, abdominal fat, and cholesterol levels.

And to help you hold back the sands of time, we recommend trying an anti-aging supplement such as Fisetin. Fisetin is an antioxidant flavonoid found at low levels in mangoes, strawberries, and persimmon. This extraordinary natural senolytic promotes the elimination of senescent cells associated with aging. Fisetin is also known for reactivating 'autophagy' – in other words, it helps rid healthy cells of harmful waste products.


Do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used as a substitute for a varied and balanced diet or a healthy lifestyle.


Store in a cool, dry place away from direct sunlight, heat, and humidity. Keep out of reach of children.


If you are pregnant, breastfeeding, or have any medical conditions, consult your healthcare provider before using this product.


Consult your healthcare provider before use, especially if you are taking any medications or other supplements as there may be potential interactions.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Need help?


Call us :
+1 (786) 522-3907
From 9 am to 6 pm (EST)

Frequently-asked questions

Find answers to the most common questions

Contact form

Can't find the answer to your question and want to contact us directly?
Write to us
Secure payment
32 Years of experience
Fast Shipping
Free shipping from $25 of purchase