Free Shipping on Orders Above $25
× SuperSmart Shop by health concern Shop by product Bestsellers New products Promotions My account Smart Prescription Blog Loyalty program Language: English
Welcome Shop by health concern Hormone health Natural Breast Formula
Natural Breast Formula
Natural Breast Formula
0807Natural Breast FormulaNatural Breast Formula
Sans nano-particulesSans glutenVegan
Natural Breast Formula
Hormone health
No reviews
Today Limited quantity
Best if used before 08/30/2022
The best natural formulation for breast health
  • High in DIM which helps increase levels of 2-hydroxyestrone (the ‘good estrogen’).
  • Contains PureSea™, a patented extract of Ascophyllum nodosum, rich in iodine and fucoxanthin.
  • Concentrated in HMRlignan™, a natural source of lignans (phytoestrogens) with anti-degenerative properties.
  • Also contains calcium D-glucarate, which facilitates the elimination of excess estrogen and thus helps correct hormone imbalances.
  • Includes powerful antioxidants (SDG from flax seed, N-acetylcysteine…) which fight against cell damage.
: 57.04 $, save $4.96 (8%)
: 57.04 $, save $4.96 (8%)
I'd like
60 Veg. Caps
Add To Cart
Natural Breast Formula

Natural Breast Formula

Natural Breast Formula is an innovative, high-quality supplement, packed with nutrients beneficial for breast health. Its various ingredients have been meticulously selected: phytonutrients that contribute to good hormonal balance and the prevention of abnormal cell growth, antioxidants that help protect cells, trace elements, vitamins, etc. Discover more about its composition and properties.

What is in the supplement Natural Breast Formula?

The excellent Natural Breast Formula contains 7 natural ingredients all chosen and dosed with the utmost precision. They are:

  1. Di-indolylmethane (DIM). This bioactive substance has been identified in cruciferous vegetables(beetroot, cauliflower, mustard greens ...) A number of studies suggest that DIM helps ensure normal estrogen metabolism. Supplementing with DIM encourages production of the ‘good’ 2-hydroxyestrone metabolites, and discourages that of the undesirable 16-hydroxyestrone metabolites (1-4);
  2. PureSea™, a patented extract of Ascophyllum nodosum, with a high iodine content. Known also as bladderwrack, Ascophyllum is a type of brown seaweed with a high nutritional content. In particular, it contains fucoxanthin, a highly sought-after pigment from the carotenoid family, which appears to combat uncontrolled cell growth (5-7);
  3. HMRlignan™, an excellent extract of Norway spruce knots. This substance is a source of the extensively-studied phenolic compounds called lignans. The body converts certain plant lignans into enterolignans, or ‘mammalian lignans’ (namely enterodiol and enterolactone). These compounds are classed as phytoestrogens: with a similar structure to that of 17-β-oestradiol (E2) (the main female sex hormone) they are able to bind to estrogen receptors. Enterolactone, for example, binds only weakly to estrogen receptors, and as a result, significantly reduces estrogenic activity. It’s worth noting too that the 7-hydroxymatairesinol in HMRlignan™ also has anti-degenerative properties (8-14);
  4. An extract of flax seed rich in secoisolariciresinol diglucoside (SDG). SDG is also an important lignan (phytoestrogen) which is becoming increasingly popular in the nutraceutical sector for its ability to combat oxidative stress. It may also have anti-proliferative and pro-apoptotic effects (15-17);
  5. Calcium D-glucarate. This calcium salt is recognized for inhibiting the enzyme beta-glucuronidase and thus facilitating the elimination of excess estrogen. Elevated beta-glucuronidase activity is also associated with abnormal cell proliferation (18-23);
  6. Vitamin D3. The ‘sunshine vitamin’ is important to human health in many ways, including supporting both normal calcium and phosphorus absorption and good immune system function. It may, in some cases, be able to stem the growth of damaged cells (24-27);
  7. And N-acetylcysteine (NAC), a precursor of the well-known amino acid L-cysteine. NAC is a powerful antioxidant which helps combat free radical proliferation and thus prevent cells from being corrupted (28-29).

What benefits are offered by Natural Breast Formula?

Benefits of Natural Breast Formula

Natural Breast Formula has been specially developed to support breast health. Supplementing with this product will increase your intake of breast-beneficial nutrients.

By encouraging production of 2-hydroxyestrone, facilitating the elimination of excess estrogen or binding to estrogen receptors, the DIM, calcium salt and enterolignans will help maintain good hormonal balance which is beneficial to breast health(30-33).

PureSea™ and HMRlignan™, along with the flax seed extract, calcium D-glucarate and vitamin D3, will also help combat the proliferation of deviant cells. Some scientific studies suggest that lignans are able, in particular, to inhibit cell migration and cell adhesion (34). The supplement Natural Breast Formula also contains numerous antioxidants: N-acetylcysteine (NAC), the phlorotannins in PureSea™, the 7-hydroxymatairesinol in HMRlignan™... By boosting the fight aganst oxidative stress, these compounds help to prevent damage to cells (35).

3 more reasons why you should try this supplement

  • The PureSea™ extract in Natural Breast Formula also contains a significant amount of iodine. As we know, this trace element supports good energy metabolism and helps maintain healthy skin and production of thyroid hormones, known for their positive effect on cells (36-37).
  • Its vitamin D3 contributes to strong immune defenses and the process of cell division (38-39). It also helps maintain blood calcium levels(40). We have chosen vitamin D3, or cholecalciferol, as it is more effective than vitamin D2 at increasing levels of 25-hydroxyvitamin D (the form present in the blood) (41). It’s worth noting that as well as causing fatigue and muscle pain, a lack of vitamin D may also have an effect at a cellular level(42-43).
  • Its N-acetylcysteine (NAC) is also a precursor of glutathione. This tripeptide molecule, which facilitates electron exchange in cells, is regarded as the best antioxidant of all(44). Glutathione is also involved in eliminating heavy metals and protecting cells from certain pollutants and toxins such as fuel and cigarettes (45).

How should you take this supplement?

The recommended dose is 2 capsules of Natural Breast Formula a day, taken with a glass of water.

Advice for maintaining optimal breast health

Here are a few practical tips to help you protect the health of your breasts:

  • stop smoking;
  • reduce your alcohol consumption, as alcohol can increase estrogen levels and thus the risk of breast problems;
  • eat plenty of high-fibre foods(raspberries, blackberries, apples, papaya, white or red beans, artichokes, cabbages, lentils, chickpeas ...) (46);
  • try to lose weight, especially if you’re going through the menopause (adipose tissue produces large amounts of estrogen in women);
  • take regular exercise;
  • avoid exposure to pesticides, herbicides, insecticides and other endocrine disruptors;
  • make sure you get screened every two years, especially if you’re over 50. This is particularly important if there are other women in your family who have suffered with breast problems, suggesting a possible genetic predisposition, or if you yourself have had concerns of this sort in the past. After examining your breasts (palpation), your doctor or gynaecologist may recommend (palpation) a mammogram, or ultrasound scan.

Supplements that work in synergy with Natural Breast Formula

Are you looking for other supplements to support good hormonal balance and healthy cells?

Why not try the excellent Natural Anti Aromatase Support. This formulation is designed to help counter the process of ‘aromatisation’ (the conversion of androgens into estrogens caused by the enzyme aromatase) and more generally, to help regulate estrogen production.

In terms of cell health, we’d suggest AntiOxidant Synergy, a supplement with a particularly high content of natural antioxidants: catechins, polyphenols, curcumin, resveratrol, etc. It’s the perfect supplement for helping to reduce oxidative stress which is damaging to health.

Daily dose: 2 capsules
Number of doses per pack: 30

per dose

Di-indolylmethane (DIM) 200 mg
PureSea™, extract of Ascophyllum nodosum standardized to 650 ppm of iodine 200 mg
HMRlignan™, extract of Norway spruce knots (Picea abies) standardized to 90% 7-hydroxymatairesinol potassium acetate complex 65 mg
Extract of flax seed standardized to 50% secoisolariciresinol diglucoside (SDG) 35 mg
Calcium D-glucarate 200 mg
Vitamin D3 1000 IU
N-acetylcysteine (NAC) 200 mg
Other ingredients: acacia gum, white rice flour.
PureSea™, Seaweed & Co, UK. HMRLignan™, Linnea S.A, Suisse.
Directions for use

Adults. Take 2 capsules a day.

Note: in the case of doses above 2000IU a day, it’s advisable to first take a 25-hydroxyvitamin D test. If you suffer from kidney disease, do not take vitamin D3 without the advice of your therapist. Do not exceed 10,000IU a day, all sources combined, except on the advice of your therapist.

No reviews for this product yet
  1. Thomson CA, Ho E, Strom MB. Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies. Nutr Rev. 2016;74(7):432-443. doi:10.1093/nutrit/nuw010
  2. Mulvey L, Chandrasekaran A, Liu K, et al. Interplay of genes regulated by estrogen and diindolylmethane in breast cancer cell lines. Mol Med. 2007;13(1-2):69-78. doi:10.2119/2006-00038.Mulvey
  3. Muti P, Bradlow HL, Micheli A, et al. Estrogen metabolism and risk of breast cancer: a prospective study of the 2:16alpha-hydroxyestrone ratio in premenopausal and postmenopausal women. Epidemiology. 2000;11(6):635-640. doi:10.1097/00001648-200011000-00004
  4. Bradlow HL, Telang NT, Sepkovic DW, Osborne MP. 2-hydroxyestrone: the 'good' estrogen. J Endocrinol. 1996;150 Suppl:S259-S265.
  5. Garg S., Afzal S., Elwakeel A., Sharma D., Radhakrishnan N., Dhanjal JK., Sundar D., Kaul SC.,1, Wadhwa R., (2019) Marine Carotenoid Fucoxanthin Possesses Anti-Metastasis Activity : Molecular Evidence. Marine drugs.
  6. Yu RX., Yu RT., Liu Z., (2018) Inhibition of two gastric cancer cell lines induced by fucoxanthin involves downregulation of Mcl-1 and STAT3. Human cell.
  7. Wang L., Zeng Y., Liu Y., Hu X., Li S., Wang Y., Li L., Lei Z., Zhang Z. (2014) Fucoxanthin induces growth arrest and apoptosis in human bladder cancer T24 cells by up-regulation of p21 and down-regulation of mortalin. Acta biochemica et biophysica Sinica.
  8. Cosentino M, Marino F, Ferrari M, et al. Estrogenic activity of 7-hydroxymatairesinol potassium acetate (HMR/lignan) from Norway spruce (Picea abies) knots and of its active metabolite enterolactone in MCF-7 cells. Pharmacol Res. 2007;56(2):140-147. doi:10.1016/j.phrs.2007.05.001
  9. Laidlaw M, Cockerline CA, Sepkovic DW. Effects of a breast-health herbal formula supplement on estrogen metabolism in pre- and post-menopausal women not taking hormonal contraceptives or supplements: a randomized controlled trial [published correction appears in Breast Cancer (Auckl). 2012;6:101]. Breast Cancer (Auckl). 2010;4:85-95. Published 2010 Dec 16. doi:10.4137/BCBCR.S6505
  10. Miura D, Saarinen NM, Miura Y, Santti R, Yagasaki K. Hydroxymatairesinol and its mammalian metabolite enterolactone reduce the growth and metastasis of subcutaneous AH109A hepatomas in rats. Nutr Cancer. 2007;58(1):49-59. doi:10.1080/01635580701308133
  11. Rietjens IMCM, Louisse J, Beekmann K. The potential health effects of dietary phytoestrogens. Br J Pharmacol. 2017;174(11):1263-1280. doi:10.1111/bph.13622
  12. Lamblin, Frédéric ; Hano, Christophe ; Fliniaux, Ophélie ; Mesnard, François ; Fliniaux, Marc-André ; Lainé, Éric ; Intérêt des lignanes dans la prévention et le traitement de cancers, Med Sci (Paris), 2008, Vol. 24, N° 5; p. 511-520 ; DOI : 10.1051/medsci/2008245511
  13. https://psychonutritionbordeaux.com/blog/endometriosepourquoieviteroufavoriserlesphytoestrogenes
  14. Bylund A, Saarinen N, Zhang JX, et al. Anticancer effects of a plant lignan 7-hydroxymatairesinol on a prostate cancer model in vivo. Exp Biol Med (Maywood). 2005;230(3):217-223. doi:10.1177/153537020523000308
  15. Kezimana P, Dmitriev AA, Kudryavtseva AV, Romanova EV, Melnikova NV. Secoisolariciresinol Diglucoside of Flaxseed and Its Metabolites: Biosynthesis and Potential for Nutraceuticals. Front Genet. 2018;9:641. Published 2018 Dec 12. doi:10.3389/fgene.2018.00641
  16. Imran M, Ahmad N, Anjum FM, et al. Potential protective properties of flax lignan secoisolariciresinol diglucoside. Nutr J. 2015;14:71. Published 2015 Jul 28. doi:10.1186/s12937-015-0059-3
  17. Li D, Yee JA, Thompson LU, Yan L. Dietary supplementation with secoisolariciresinol diglycoside (SDG) reduces experimental metastasis of melanoma cells in mice. Cancer Lett. 1999;142(1):91-96. doi:10.1016/s0304-3835(99)00158-5
  18. Calcium-D-glucarate. Altern Med Rev. 2002;7(4):336-339.
  19. Singh J, Gupta KP. Induction of apoptosis by calcium D-glucarate in 7,12-dimethyl benz [a] anthracene-exposed mouse skin. J Environ Pathol Toxicol Oncol. 2007;26(1):63-73. doi:10.1615/jenvironpatholtoxicoloncol.v26.i1.70
  20. WHITAKER BL. Plasma beta-glucuronidase levels in breast cancer. Br J Cancer. 1960;14(3):471-477. doi:10.1038/bjc.1960.51
  21. http://assasmus.s.a.f.unblog.fr/files/2013/11/336-pdf-calcium-d-glucarate.pdf
  22. Dwivedi C, Heck WJ, Downie AA, Larroya S, Webb TE. Effect of calcium glucarate on beta-glucuronidase activity and glucarate content of certain vegetables and fruits. Biochem Med Metab Biol. 1990;43(2):83-92. doi:10.1016/0885-4505(90)90012-p
  23. Walaszek Z, Szemraj J, Narog M, et al. Metabolism, uptake, and excretion of a D-glucaric acid salt and its potential use in cancer prevention. Cancer Detect Prev. 1997;21(2):178-190.
  24. Chauhan K, Shahrokhi M, Huecker MR. Vitamin D. [Updated 2020 May 6]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441912/
  25. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1227
  26. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1468
  27. Garland CF, Garland FC, Gorham ED, et al. The role of vitamin D in cancer prevention. Am J Public Health. 2006;96(2):252-261. doi:10.2105/AJPH.2004.045260
  28. Tardiolo G, Bramanti P, Mazzon E. Overview on the Effects of N-Acetylcysteine in Neurodegenerative Diseases. Molecules. 2018;23(12):3305. Published 2018 Dec 13. doi:10.3390/molecules23123305
  29. Monti D, Sotgia F, Whitaker-Menezes D, et al. Pilot study demonstrating metabolic and anti-proliferative effects of in vivo anti-oxidant supplementation with N-Acetylcysteine in Breast Cancer. Semin Oncol. 2017;44(3):226-232. doi:10.1053/j.seminoncol.2017.10.001
  30. Thomson CA, Ho E, Strom MB. Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies. Nutr Rev. 2016;74(7):432-443. doi:10.1093/nutrit/nuw010
  31. Calcium-D-glucarate. Altern Med Rev. 2002;7(4):336-339.
  32. Lamblin, Frédéric ; Hano, Christophe ; Fliniaux, Ophélie ; Mesnard, François ; Fliniaux, Marc-André ; Lainé, Éric ; Intérêt des lignanes dans la prévention et le traitement de cancers, Med Sci (Paris), 2008, Vol. 24, N° 5; p. 511-520 ; DOI : 10.1051/medsci/2008245511
  33. https://psychonutritionbordeaux.com/blog/endometriosepourquoieviteroufavoriserlesphytoestrogenes
  34. Buck K, Vrieling A, Zaineddin AK, et al. Serum enterolactone and prognosis of postmenopausal breast cancer. J Clin Oncol. 2011;29(28):3730-3738. doi:10.1200/JCO.2011.34.6478
  35. Lobo V, Patil A, Phatak A, Chandra N. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn Rev. 2010;4(8):118-126. doi:10.4103/0973-7847.70902
  36. Ahad F, Ganie SA. Iodine, Iodine metabolism and Iodine deficiency disorders revisited. Indian J Endocrinol Metab. 2010;14(1):13-17.
  37. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1214
  38. Chauhan K, Shahrokhi M, Huecker MR. Vitamin D. [Updated 2020 May 6]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441912/
  39. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2009.1227
  40. https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1468
  41. Trang HM, Cole DE, Rubin LA, Pierratos A, Siu S, Vieth R. Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2. Am J Clin Nutr. 1998;68(4):854-858. doi:10.1093/ajcn/68.4.854
  42. Atoum M, Alzoughool F. Vitamin D and Breast Cancer: Latest Evidence and Future Steps. Breast Cancer (Auckl). 2017;11:1178223417749816. Published 2017 Dec 20. doi:10.1177/1178223417749816
  43. Nair R, Maseeh A. Vitamin D: The "sunshine" vitamin. J Pharmacol Pharmacother. 2012;3(2):118-126. doi:10.4103/0976-500X.95506
  44. BIOCHEMICAL PHARMACOLOGY 47 : 2113-2123, 1994
  46. Chen S, Chen Y, Ma S, et al. Dietary fibre intake and risk of breast cancer: A systematic review and meta-analysis of epidemiological studies. Oncotarget. 2016;7(49):80980-80989. doi:10.18632/oncotarget.13140

Featured products

Daily 3® SupplementDaily 3® Multivitamin Supplement

The most complete multivitamin supplement you can take in a single capsule

4.5 4 reviews
Lactobacillus Gasseri SupplementLactobacillus Gasseri Probiotic Supplement

A probiotic strain that’s particularly effective for weight control In gastroresistant DR Caps™ for optimum efficacy.

4.5 3 reviews
H. Pylori Fight Supplement H. Pylori Fight

The natural treatment for Helicobacter pylori

5 15 reviews
Melatonin SprayMelatonin Spray

All the efficacy of prolonged-release melatonin in a convenient, metered-dose, sublingual spray.

0 No reviews
Berberine SupplementBerberine

A natural and powerful new weapon against type II diabetes

5 5 reviews
Senolytic Complex Supplement Senolytic Complex

Senolytics: a revolutionary formula for destroying the senescent cells responsible for aging

5 2 reviews
Vitamin D3 Supplement Vitamin D3 5000 IU

To help prevent the risks of vitamin D deficiency Fat-soluble vitamin in oil form = increased bioavailability

0 No reviews
Super Omega 3Super Omega 3

EPA and DHA: one of the most natural, pure, powerful and stable product on the market

0 No reviews
Subscribe to our newsletter
and obtain a 5% permanent discount
Our selection of articles
How can you increase your progesterone levels naturally?

During the menopause, there’s a fall in progesterone, resulting in a variety of unpleasant symptoms. Here are some natural ways in which you can re-elevate it.

4 natural products for taking care of your thyroid

Though very small, the thyroid gland plays a critical part in ensuring the body functions correctly, so it’s vitally important to look after it. Discover 4 natural compounds beneficial for the health of this key endocrine gland.

What if you were simply deficient in iodine?

Though it’s rarely discussed, iodine deficiency is a relatively common problem. Here’s a brief overview of its symptoms and ways of addressing it.

Natural Breast Formula
$62.00$18.60* Add To Cart
© 1997-2022 Fondation pour le Libre Choix. All rights reserved
© 1997-2022 Fondation pour le Libre Choix. All rights reserved