Eye Wellness is a dietary supplement formulated with two patented botanical extracts: MirtoSelect®, a standardized bilberry (Vaccinium myrtillus) extract, and Pycnogenol®, a standardized French maritime pine bark (Pinus pinaster) extract. Naturally rich in polyphenols, including anthocyanins and proanthocyanidins, this formula is designed to complement a balanced diet and support a daily eye wellness routine.*
Who Is Eye Wellness Intended For?
This botanical formula is intended for adults looking to complement a balanced lifestyle with carefully selected plant extracts traditionally used in eye wellness routines.*
- Adults wishing to incorporate botanical polyphenols into their daily nutritional routine.
- Those interested in supplements featuring standardized bilberry and pine bark extracts.
- Individuals seeking nutritional support as part of their overall eye wellness routine.*
- Anyone looking for high-quality botanical ingredients sourced from Europe.
What Is MirtoSelect®?
MirtoSelect® is a premium bilberry extract (Vaccinium myrtillus) standardized to provide 36% anthocyanins. It is produced exclusively from ripe European bilberries harvested during the summer season using carefully controlled manufacturing processes designed to preserve the naturally occurring plant compounds.
Bilberry has been traditionally valued in Europe for centuries and continues to be widely studied for its naturally occurring polyphenols, particularly anthocyanins. These pigments belong to the flavonoid family and are responsible for the fruit's characteristic dark blue color.
Anthocyanins occur naturally in a variety of fruits and vegetables, although bilberries are among their richest natural dietary sources. They have attracted considerable scientific interest because of their antioxidant properties and their role as naturally occurring plant compounds.
Anthocyanins Naturally Present in Bilberries
Anthocyanins are members of the flavonoid family of polyphenols and contribute to the distinctive color of many berries, grapes, and other fruits. These compounds are naturally present in bilberries in particularly high concentrations.
Research continues to explore the biological characteristics of anthocyanins and their interactions with normal physiological processes. Their antioxidant properties have made them one of the most extensively studied groups of plant-derived compounds.
Note: Bilberry (Vaccinium myrtillus) should not be confused with cultivated blueberry species. Bilberries are wild European berries characterized by their dark blue flesh and naturally high anthocyanin content.
How Is MirtoSelect® Produced?
MirtoSelect® is produced from carefully selected wild European bilberries harvested at peak ripeness. After harvesting, the berries are processed under controlled conditions to preserve their naturally occurring polyphenols while ensuring consistent quality and standardization.
Standardization allows each batch to provide a consistent anthocyanin content, supporting product quality from one production lot to another.
WARNINGS
Do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used as a substitute for a varied and balanced diet or a healthy lifestyle.
STORAGE
Store in a cool, dry place away from direct sunlight, heat, and humidity.
Keep out of reach of children.
PREGNANCY AND MEDICAL CONDITIONS
If you are pregnant, breastfeeding, or have any medical conditions, consult your healthcare provider before using this product.
SUPPLEMENT INTERACTIONS
Consult your healthcare provider before use, especially if you are taking any medications or other supplements as there may be potential interactions.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Serving Size: 1 Capsule
Servings Per Container: 30 |
Amount
Per Serving |
| Vitamin E (as d-alpha tocopheryl acetate) |
75 mg* |
Mirtoselect®
Bilberry Extract (Vaccinium myrtillus) Standardized to 36% Anthocyanins |
70 mg |
Pycnogenol®
French Maritime Pine Bark Extract |
40 mg |
Other Ingredients: Pullulan (capsule) and Acacia Gum.
*DV: Vitamin E 500%.
Mirtoselect®, Indena, Italy. Pycnogenol®, Horphag, Switzerland.
|
Serving size: Take 1 capsule a day.
Servings per container: 30
Storage: Store away from direct light, heat, and humidity.
Cautions: For adults only. Do not exceed the recommended daily dose. Keep out of reach of children. Consult a healthcare provider before taking this supplement and if you are pregnant, breastfeeding, or having health concerns.*
This product is a dietary supplement and should not be used as a substitute for a varied, balanced diet and a healthy lifestyle.
- Kim E.S., J. Clinical Evaluation of Patients with Nonproliferative ... Following Medication of ... : Multicenter Study, Korean Ophthalmology Soc., 2008;49(10):1629-1633.
- Mazzolani F. et al., The effect of oral supplementation with standardized bilberry extract (Mirtoselect®) on retino-cortical bioelectrical activity in ... , Minerva Oftalmol 2017 June;59(2)_38-41
- Riva A, Togni S et al. The effect of a natural, standardized bilberry extract (Mirtoselect®) in ... eye: a randomized, double blinded, placebo-controlled trial. Eur Rev Med Pharmacol Sci. 2017 May;21(10):2518-2525.
- Kajimoto O, Sasaki K, Takahashi T. Recovery effect of VMA intake on visual ... in primary school students. J New Rem & Clin 2000;49:72-79. [Article in Japanese]
- Virno M, Pecori Giraldi J, Auriemma L. Antocianosidi di mirtillo e permeabilità dei vasi del corpo ciliare. Boll Ocul. 1986;65:789–95.
- Karlsen A et al. Anthocyanins Inhibit Nuclear Factor-kB Activation in Monocytes and ... in Healthy Adults, J. Nutr. 2007, 137, 1951-1954.
- Nutrient U.S. Department of Agriculture, A.R.S., USDA Database for the Flavonoid Content of Selected Foods, Release 3.0 2011.
- Shumin Li, Adam J. Case et al. Over-expressed copper/zinc superoxide dismutase localizes to mitochondria in neurons inhibiting the angiotensin II-mediated increase in mitochondrial superoxide, Redox Biol. 2014; 2: 8–14. Published online 2013 Nov 18. doi: 10.1016/j.redox.2013.11.002
- Sparrow JR, Vollmer-Snarr HR, Zhou J, Jang YP, Jockusch S, Itagaki Y, Nakanishi K. A2E-epoxides ... DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation. J. Biol. Chem., Vol. 278, Issue 20, 18207-18213 (2003).
- Sparrow JR, Vollmer-Snarr HR, Zhou J, Jang YP, Jockusch S, Itagaki Y, Nakanishi K. A2E-epoxides ... DNA in retinal pigment epithelial cells. Vitamin E and other antioxidants inhibit A2E-epoxide formation. J. Biol. Chem., Vol. 278, Issue 20, 18207-18213 (2003).
- Yao N. ... effects of bilberry (Vaccinium myrtillus L.) extract ... in mice. J. Agric. Food Chem., 2010, 58 (8), pp 4731–4736.
- Chen, Jihua, Uto, Takuhiro, Tanigawa, Shunsuke, Kumamoto, Takuma, Fujii, Makoto and Hou, De-Xing. “Expression Profiling of Genes Targeted by Bilberry (Vaccinium myrtillus) in Macrophages Through DNA Microarray”, Nutrition and ... , 60:1,43 – 50 (2008)
- Perretti C, Magistretti MJ, Robotti A, Ghi P, Genazzani E (1988) Vaccinium myrtillus anthocyanosides are inhibitors of AMPc and GM-Pc phosphodiesterases Pharmacol Res Comm 20(Suppl 2) 150 (PDF) Different brands of bilberry extract: A comparison of selected components. Available from: https://www.researchgate.net/publication/242267405_Different_brands_of_bilberry_extract_A_comparison_of_selected_components [accessed Jun 27 2018].
- Piovella F., Ricetti M. M., Almasio P., Feoli F. R., Pesenti Campagnoni M., Castagnola C., Min. Angiol. 6, 135 (1981)
- Prior R.L. et al., Antioxidant Capacity As Influenced by Total Phenolic and Anthocyanin Content, Maturity, and Variety of Vaccinium Species, J. Agric. Food Chem. 46, 2686 (1998).
- Desmettre T. Stress oxydant et DMLA. Réalités ophtalmologiques 2004 ; n° 111.
- Sundelin S, Wihlmark U, Nilsson SE, Brunk UT. Lipofuscin accumulation in cultured retinal pigment epithelial cells reduces their ... capacity. Curr Eye Res 1998 ; 17 : 851-7.
- Rozanowska M, Wessels J, Boulton M, Burke JM, Rodgers MA, Truscott TG, et al. Blue light-induced singlet oxygen generation by retinal lipofuscin in non-polar media. Free Radic Biol Med 1998 ; 24 : 1107-12
- Boulton M, Dontsoy A, Jarvis-Evans J, Ostrovsky M, Svistunenko D. Lipofuscin is a photoinductible free radical generator. J Photochem Photobiol 1993 ; 19 : 201-4.
- Eldred GE. Lipofuscin fluorophore inhibits lysosomal protein degradation and may cause early stages of macular ... . Gerontology 1995 ; 41 (Suppl. 2) : 15-28.
- Beatty S, Koh H, Phil M, Henson D, Boulton M. The role of oxidative stress in the ... . Surv Ophtalmol 2000 ; 45 : 115-34
- Kuroki M, Voest EE, Amano S, Beerepoot LV, Takashima S, Tolentino M, et al. Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo. J Clin Invest 1996 ; 98 : 1667-75.
