Fumaric Acid Supplement - Combat the Discomfort of Psoriasis

This fumaric acid supplement contains a molecule that may help relieve the effects of psoriasis, such as itching and inflammation. A little-known molecule, fumaric acid, is naturally present in all living organisms. In humans, it is produced in the skin by a mechanism similar to that of Vitamin D.

And like Vitamin D, fumaric acid is produced through exposure to the sun. But in psoriasis sufferers, this endogenous production is impaired. Fumaric acid supplementation was therefore first studied with the intention of correcting this deficiency. Researchers investigating the effects of such supplementation subsequently found that fumaric acid did indeed combat the negative effects of psoriasis.

What is Psoriasis?

Psoriasis is a chronic skin condition that remains poorly understood. According to current scientific data, the risk of developing psoriasis may be due to genetic predisposition, but it may also be triggered by other factors, such as stress, emotional shock, use of certain drugs, hormone imbalances, and infections.

Particularly prevalent in industrialized countries, this skin condition develops in cycles. During attacks, thick, red, dry, and itchy patches of skin appear on the body. Though psoriasis is benign, it is nonetheless extremely troublesome, unpleasant, and causes discomfort. There is also no current long-term solution for psoriasis, which is why so many people turn to fumaric acid to combat its effects.

Benefits of Fumaric Acid for Skin Care

Fumaric acid skin benefits are well researched and are shown to provide an array of support. If you are considering using fumaric acid for psoriasis, you’ll want to read the following studies:

• A number of studies suggest fumaric acid's benefits are because of its immune regulating properties. It combats several immune system disorders, including those involved in psoriasis.
• It may, in particular, reduce the chronic inflammation and abnormal renewal of keratinocyte epidermal cells typically associated with the condition, according to some research. In countering these two mechanisms, fumaric acid acts as an inhibitor to psoriasis.
• The therapeutic potential of fumaric acid supplementation was first recognized several decades ago. At the end of the 1950s, a German biochemist suggested that deficiency in fumaric acid played a role in the presence of psoriasis attacks.
• In the 1980s, a German doctor proved this hypothesis and developed an oral supplement to combat psoriasis from fumaric acid derivatives. For over 30 years, oral use of fumaric acid and its derivatives has continued to demonstrate their potential in beneficial effects in calming the itching and scaly skin, and the general discomfort associated with psoriasis.
• Fumaric acid supplementation has been successfully used for several decades in Europe and the U.S. Its safety has been evaluated and confirmed by the US public health body, the Food and Drug Administration (FDA), which has added fumaric acid to its list of GRAS (Generally Recognized As Safe) substances.

Further fumaric acid uses may be evaluated in future studies.

Additional Fumaric Acid Benefits

Aside from the fumaric acid health benefits for your skin, it might be used for other purposes as well. In fact, there is research suggesting that fumaric acid may be beneficial for use with other immunity issues through a mechanism that detoxifies radicals and supports nerve and glial cells.

Potential Fumaric Acid Side Effects

Before you buy fumaric acid supplements, you should evaluate your health with a licensed medical professional. Fumaric acid capsules are generally regarded as a safe, natural alternative to medicine, but every individual reacts differently to them. That's why it's essential to do your own research before starting a new fumaric acid regimen — or a regimen for any other supplement.

It's important to talk to your healthcare provider to find out whether or not fumaric acid may negatively interact with any specific health conditions or prescription medications. If you start to notice unusual side effects while taking any supplement, you should immediately discontinue use until you have discussed, and received approval to continue your regimen from your primary care provider.

There's not enough research to determine if taking fumaric acid while pregnant or breastfeeding is safe. That's why we recommend avoiding it at these times. It is also not intended for use by children.

How to Take Fumaric Acid

We recommend healthy adults take one of our fumaric acid vegan capsules a day, ideally before breakfast and with plenty of fluid. If you have any specific health conditions or take any specific prescription medications, be sure to confirm the recommended serving size with your doctor.

If you consume one capsule a day, one bottle will last you 90 days, or three months. In cases of severe psoriasis, you may need to use fumaric acid for longer than only a 90-day period. It is perfectly safe to take fumaric acid for longer than 90 days as long as you consult your doctor. Each capsule contains fumaric acid, rice flour, and acacia gum. There are no other ingredients and no fillers.

When you’re looking at where to buy fumaric acid, be sure and take into consideration the quality of the source, as not all supplements are the same level of quality. It's critical that you trust the company you purchase from. If you are unsure what is in a supplement, ask to see third-party testing.

Be sure to store all supplements in a cool, dry location out of direct sunlight. Additionally, you should always dispose of supplements when they reach their "best by" or expiration date. After that date, supplements begin to lose their efficacy.

1. Roa Engel CA, Straathof AJ, Zijlmans TW, van Gulik WM, van der Wielen LA. Fumaric acid production by fermentation. Appl Microbiol Biotechnol. 2008;78(3):379-389. doi:10.1007/s00253-007-1341-x
2. Kamiya K, Kishimoto M, Sugai J, Komine M, Ohtsuki M. Risk Factors for the Development of Psoriasis. Int J Mol Sci. 2019;20(18):4347. Published 2019 Sep 5. doi:10.3390/ijms20184347
3. Schilling S, Goelz S, Linker R, Luehder F, Gold R. Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration. Clin Exp Immunol. 2006;145(1):101-107. doi:10.1111/j.1365-2249.2006.03094.x
4. Kokelj F, Plozzer C, Avian A, Trevisan G. Fumaric acid and its derivatives in the treatment of psoriasis vulgaris: our experience in forty-one patients. Acta Dermatovenerol Croat. 2009;17(3):170-175.
5. Haghikia A, Linker R, Gold R. Fumarsäure in der Therapie der Multiplen Sklerose [Fumaric acid as therapeutic agent for multiple sclerosis]. Nervenarzt. 2014;85(6):720-726. doi:10.1007/s00115-014-4005-y