It’s true that omega-3 fatty acids, particularly those contained in fish oil supplements, are best absorbed by the body when taken alongside a high-fat meal (1). It’s also better to take them at the start of the meal, to prevent any potential gastric problems.
A lipid-rich meal stimulates the production of bile acids: produced by the liver, these help to emulsify essential long-chain fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These are the main omega-3 fatty acids found in the various omega-3 supplements available (fish oil, krill oil, calanus oil...).
Once emulsified in this way, the long-chain fatty acids are easier to digest by lipases, pancreatic enzymes which act at the upper level of the intestine (2) and which facilitate their absorption.
Some marine-source omega-3 supplements can produce adverse effects such as burping, acid reflux, bad breath, and a fishy after-taste … Such effects are mainly due to undue oxidation (3) of the fatty acids. To some degree, oxidation is normal, but it can become excessive during the various production and preservation stages of fish oil-based supplements.
To avoid these effects, be sure to choose supplements of EPA and DHA fatty acids in their natural form (triglycerides). It’s more expensive than the synthetic form (ethylic esters), but studies show that it’s easier to digest (there’s no release of ethanol) and twice as bioavailable. It’s a good idea to choose supplements that contain antioxidants too, especially tocopherols (ie, vitamin E), to minimise oxidation and maximise preservation.
In addition, taking these supplements at the start of a meal reduces the time they take to pass through the stomach and thus minimises the risk of unwelcome gastric effects.
EPA and DHA have proven beneficial effects:
In the case of therapeutic use, it’s essential to seek advice from your pharmacist in order to take the right dose for your particular situation.
The oil obtained from this small shrimp-like crustacean has swept the globe since the development of a particular oil extraction technique in the 2000s. Let’s take a close look at krill and its benefits.
Hypertension: an often-silent disease with serious consequences. Here’s our guide to the best plants for controlling it!
Heavy legs, varicose or dilated veins... phytotherapy and good plant combinations are an effective solution to the problem of venous insufficiency.
It’s vital to take care of your arteries in order to reduce the risk of serious cardiovascular problems. Read on for our list of 8 recommendations to apply each day!
Though most people are aware of vitamin K, it’s less well-known that there are actually two main forms of this vitamin: phylloquinone (K1) and menaquinone (K2). Do you know the differences between them?
Which is more effective – coenzyme Q10 or ubiquinol?