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These nutrients are much better absorbed thanks to black pepper

Several scientific studies have shown that certain nutrients are much better absorbed by the body in the presence of black pepper. Find out how this condiment can boost your diet and the bioavailability of your supplements.

Black pepper to absorb nutrients

Black pepper (Piper nigrum): a spice with amazing properties

Black pepper (Piper nigrum) is much more than just a spice used to season dishes; it supports the appetite, digestion and the absorption of nutrients.

Black pepper contains a major active ingredient: piperine, an alkaloid that gives it its characteristic flavour and, above all, unique properties in terms of nutritional assimilation.

But how exactly does it work?

Although the exact mechanisms of its action are still being studied, piperine is thought to modulate certain digestive enzymes and intestinal transport proteins, and to slow down the hepatic degradation (i.e. alteration during passage through the liver) of many active compounds.

It could also increase the permeability of intestinal membranes, facilitating the passage of molecules into the bloodstream.

The result: several nutrients and phytoactive compounds are more bioavailable when taken with piperine (i.e. black pepper).

Nutrients better absorbed with black pepper

Curcumin: a powerful anti-inflammatory agent

Curcumin (the active molecule in turmeric) is known for its antioxidant and anti-inflammatory properties. The problem is that it is rapidly metabolised by the liver and is poorly absorbed by the body when taken on its own.

However, several years ago, a landmark study showed that piperine improves the serum concentration, degree of absorption and bioavailability of curcumin in humans (1).

Curcumin supplements therefore benefit from being combined with a piperine-standardised black pepper supplement.

  • Discover the Super Curcuma food supplement, which offers 29 times greater absorption of curcuminoids than conventional products.

Beta-carotene: a precursor of vitamin A

Beta-carotene is a precursor of vitamin A, which has multiple benefits.

In particular, it contributes to the normal functioning of the immune system and helps maintain normal eyesight, skin and mucous membranes. It also contributes to the normal metabolism of iron.

However, beta-carotene is sensitive to heat and oxidation, and is sometimes poorly absorbed.

Piperine supplementation significantly improves serum beta-carotene levels, suggesting better intestinal assimilation and stabilisation of the compound (2). It is therefore advisable to combine it with a beta-carotene dietary supplement.

  • Discover Carottol dietary supplement, a precious complex of natural carotenoids.

Iron: essential for the production of red blood cells

Iron is a trace element essential for the body to function properly. In particular, it contributes to the normal formation of red blood cells and haemoglobin.

But its bioavailability is often low, particularly in its non-heme form (i.e. that found in plant-based foods).

Targeted supplementation may be recommended in the event of iron deficiency, once this has been confirmed by a blood test.

  • Discover the Iron Bisglycinate supplement, which is easily absorbed by the intestine and perfectly tolerated, unlike other types of formulation.

A recent study also showed that piperine could promote intestinal absorption of iron, by inhibiting the factors that slow down its assimilation and modulating gastric acid secretion (3).

Selenium: a powerful trace element

Selenium is a key trace element. In particular, it helps to protect cells against oxidative stress and contributes to the normal functioning of the immune system and thyroid function.

Its organic form (L-selenomethionine) is better absorbed by the body than the traditional inorganic forms (selenite and selenium sulphide).

  • Find out more about the Selenium food supplement based on L-selenomethionine.

At the same time, a study shows that piperine also improves intestinal absorption of selenium by slowing down its metabolism (5).

Coenzyme Q10 (CoQ10): for cellular energy production

Coenzyme Q10 is a fat-soluble molecule naturally produced by the human body. In our bodies, it is involved in the production of cellular energy.

While the amount of endogenous CoQ10 decreases with age, it can also be obtained from external sources such as certain foods (meat, fish, nuts, etc.) and food supplements.

  • Discover the Coenzyme Q10 food supplement, which contains a combination of tocopherols and lipids to maximise its absorption.

However, you should be aware that CoQ10's low solubility makes it difficult to absorb.

But here too, a study suggests that consumption of piperine significantly increases plasma levels of CoQ10 in supplemented individuals (5).

Resveratrol: an anti-ageing polyphenol

A natural substance studied for its potential anti-ageing effects, resveratrol is a polyphenol found in grapes.

Resveratrol is being researched for its supposed antioxidant and cardioprotective effects, and is now readily available as a dietary supplement.

  • Discover the Resveratrol dietary supplement, a powerful, natural compound extracted from two plant species: Vitis vinifera and Polygonum cuspidatum.

A clinical study found that piperine improves cerebral absorption of resveratrol, which unfortunately has low oral bioavailability, resulting in positive effects on blood circulation and cognition (7).

Why is black pepper a powerful nutritional ally?

Black pepper doesn't just enhance the flavour of our dishes: thanks to piperine, it improves the absorption of many nutrients.

A real 'assimilation booster', black pepper is an invaluable ally for anyone who wants to get the most out of their food or maximise the effectiveness of their food supplements.

Although pepper is usually consumed as a spice, the quantities of piperine used in studies are often greater than those provided by the diet. Hence the importance of turning to concentrated, standardised and safe forms.

  • Discover Bioperine dietary supplement, standardised to 95% natural piperine.

Well tolerated, piperine helps increase the bioavailability of many micronutrients and aids digestion. It can be taken as a supplement to a healthy, balanced diet, or combined with other food supplements (as mentioned above).

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References

  1. Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998 May;64(4):353-6. doi: 10.1055/s-2006-957450. PMID: 9619120.
  2. Badmaev, V., Majeed, M. and Norkus, P.E. (1999) Piperine, An Alkaloid Derived from Black Pepper Increases Serum Response of Beta-Carotene during 14-Days of Oral Beta-Carotene Supplementation. Nutrition Research, 19, 381-388.
  3. Fernández-Lázaro D, Mielgo-Ayuso J, Córdova Martínez A, Seco-Calvo J. Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (Bioperine®) and Potential Applications. Nutrients. 2020 Jun 24;12(6):1886. doi: 10.3390/nu12061886. PMID: 32599787; PMCID: PMC7353321.
  4. Ajazuddin, Alexander A, Qureshi A, Kumari L, Vaishnav P, Sharma M, Saraf S, Saraf S. Role of herbal bioactives as a potential bioavailability enhancer for Active Pharmaceutical Ingredients. Fitoterapia. 2014 Sep;97:1-14. doi: 10.1016/j.fitote.2014.05.005. Epub 2014 May 23. PMID: 24862064.
  5. Ajazuddin, Alexander A, Qureshi A, Kumari L, Vaishnav P, Sharma M, Saraf S, Saraf S. Role of herbal bioactives as a potential bioavailability enhancer for Active Pharmaceutical Ingredients. Fitoterapia. 2014 Sep;97:1-14. doi: 10.1016/j.fitote.2014.05.005. Epub 2014 May 23. PMID: 24862064.
  6. Badmaev V, Majeed M, Prakash L. Piperine derived from black pepper increases the plasma levels of coenzyme Q10 following oral supplementation. J Nutr Biochem. 2000 Feb;11(2):109-13. doi: 10.1016/s0955-2863(99)00074-1. PMID: 10715596.
  7. Wightman EL, Reay JL, Haskell CF, Williamson G, Dew TP, Kennedy DO. Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in human subjects: a randomised, double-blind, placebo-controlled, cross-over investigation. Br J Nutr. 2014 Jul 28;112(2):203-13. doi: 10.1017/S0007114514000737. Epub 2014 May 7. PMID: 24804871.

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