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UC II® Supplement

UC II® Supplement to Alleviate Joint Pain Issues

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Undenatured type II collagen supplement.

  • Known for relieving joint pain.
  • May improve healing.
  • Antioxidant, anti-inflammatory, and analgesic effects.

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60 Veg. Caps.



60 Veg. Caps.



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UC II® Supplement

No controversial excipients
No sweeteners
No added sugars
  • Description
  • Composition
  • Directions for use

Type II collagen, a triple helical molecule, is the principal structural protein in cartilage, responsible for its resistance to traction and its endurance. Sometimes, the body's immune system confuses articular type II collagen with a foreign invader and sends antibodies to attack and destroy it, resulting in deterioration of joint flexibility and mobility. When the body attacks itself in this way, it is referred to as an auto-immune disease.

Studies from Harvard University Medical School have shown that low doses (10 mg or less) of undenatured type II collagen, derived from chicken cartilage, act in conjunction with the immune system to prevent such attacks on the joints by the body.

A study was conducted on 28 patients suffering from severe rheumatoid polyarthritis. Supplementation with undenatured type II collagen for three months produced significant improvements in their condition and four of them were totally cured (Science, 261: 1727-1730, 1993).

Following three months' treatment with undenatured type II collagen, 8 out of 10 patients suffering from juvenile rheumatoid polyarthritis saw a decrease in swelling and sensitivity in their joints (Arthritis and Rheumatism, 39:623-628, 1996).

A total of 8 clinical human studies have shown the efficacy of undenatured type II collagen in treating arthritis.

UC-II® is the only patented form of undenatured (native) type II collagen. Type II collagens usually found in nutritional supplements are denatured or hydrolyzed – in other words, their molecular configuration has been altered, rendering them inactive. According to David Trentham, a Harvard scientist and world authority on type II collagen, "to be effective, type II collagen must be in its native form."

UC-II® also contains small amounts of glucosamine and chondroitin, equally good for the joints.

Taken orally, UC-II® works with the immune system to promote healthy joints through a process called oral tolerance. This process helps the body differentiate between foreign invaders, such as bacteria or viruses, and beneficial elements, such as nutrients. Low doses of UC-II® taken orally stop the immune response that targets type II collagen in bone joint cartilage, thereby improving joint mobility and flexibility.

UC-II® thus appears to be an excellent solution for stemming decreased collagen in cartilage. Another supplement for maintaining joint health is L-Proline, an amino acid which supports the body's natural production of collagen. If you suffer from joint pain, you may find our Palmitoleic acid supplement, an omega-7 fatty acid, known for its pain-relieving effects.

UC II Collagen Supplement Side Effects

Before incorporating a UC II supplement into your diet, are there any serious side effects you need to be aware of?

UC-II collagen side effects have been documented as mild and relatively rare, making this a safe supplement to take for the vast majority of people.

However, we always recommend taking charge of your health. Do your research into this anti-inflammatory supplement first. Examine the wealth of scientific evidence available on collagen UC II 40 mg and ask others who have already taken this supplement about their experiences.

These joint pain capsules are beneficial for most people, but if you are already taking prescription medications for acute or chronic conditions, consult your doctor.

Adverse drug interactions are one of the leading causes of side effects with any supplement. Scheduling an appointment with your doctor is the only way to ensure that UC II collagen will not lead to any uncomfortable or unpleasant side effects.

Make sure you monitor your health when consuming this joint pain supplement, and do not be afraid to seek medical attention if you experience any side effects.


Do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used as a substitute for a varied and balanced diet or a healthy lifestyle.


Store in a cool, dry place away from direct sunlight, heat, and humidity. Keep out of reach of children.


If you are pregnant, breastfeeding, or have any medical conditions, consult your healthcare provider before using this product.


Consult your healthcare provider before use, especially if you are taking any medications or other supplements as there may be potential interactions.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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