Alcohol Detox Supplement to Help With Liver Protection

Alcohol Detox capsules contain a combination of ingredients that act synergistically against the damaging effects of alcohol consumption. You can buy this new formulation from Supersmart, with improved benefits from adding asparagine, Picrorhiza kurroa, and kudzu to boost its efficacy further. Combined in a single capsule, this concentrate of active principles can help regenerate and protect the liver, especially against the harmful effects of alcohol.

Why take Alcohol Detox?

Acetaldehyde, a by-product of alcohol metabolism by the liver, is thirty times more toxic than alcohol itself. It encourages the formation of crosslinks between glucose and proteins, a process known as 'glycation'. Alcohol metabolism also significantly increases free radical production, which, if left unchecked by antioxidants, results in major oxidative stress. Alcohol consumption can cause a massive drop in levels of numerous micronutrients:

• Folates, vitamins B1, B6, PP, D, and E are the first to come under attack.
• The fall in vitamin C levels, the main water-soluble antioxidant, results in serious oxidative stress in heavy drinkers and a lower concentration of endogenous antioxidant enzymes – superoxide dismutase, catalase, and glutathione peroxidase.
• Deficiencies in thiamine appear to be responsible for the degeneration of cerebellum cells, a problem affecting alcoholics.

What are the benefits of Alcohol Metabolism Supplements?

Silymarin restores glutathione levels while Sodium Rlipoate is involved in glutathione recycling.

Sodium Rlipoate and thiamine, sulfur-based nutrients, also contribute to the detoxification of acetaldehyde.

Vitamin C is crucial in protecting brain cells against alcohol-induced oxidative damage. Combined with Vitamin C, thiamine protect against acetaldehyde toxicity.

Benfotiamine, a fat-soluble thiamine derivative, prevents and slows down acetaldehyde-induced glycation. Simultaneous supplementation with fat-soluble benfotiamine and water-soluble thiamine is essential to prevent some of the more harmful effects of chronic alcohol consumption.

Administration of asparagine reduces blood concentrations of acetaldehyde by over 30%, preventing alcohol toxicity.

Extract of Picrorhiza Kurroa stimulates liver regeneration. Studies suggest it is effective at protecting the liver from biochemical changes caused by a number of toxins.

Kudzu contains flavonoids (puerarin, diazine, and daidzein) which help reduce damage from excessive alcohol consumption. They appear to act by inducing the activity of alcohol dehydrogenase (ADH), thus reducing the concentration of alcohol in the body.

Silymarin, extracted from milk thistle, has liver-protective properties; its primary use is in treating alcohol-related liver damage, but it also stimulates the regeneration of liver cells and production of liver proteins. It acts as a potent antioxidant, protects against ethanol-induced oxidative stress in the liver and hepatocytes from alcohol-induced damage, prevents fibrosis which contributes to the development of cirrhosis, and reduces mortality rates in cirrhosis patients.

For optimal liver protection, you may also be interested in a powerful and natural chelator called Zeolite Clinoptilolite, available to buy at Supersmart. Studies suggest this compound can reduce the body's alcohol absorption by around 40%.

When Should I Take Anti-Alcohol Supplements?

Alcohol is a toxin for the body, which is why alcohol has been linked with so many severe diseases. Alcohol detox capsules are designed to help the liver repair and regenerate. But when should you take this type of supplement?

A supplement for alcohol detox is designed to combat the effects of alcohol. They support your detox by making it easier to cope with the effects of giving up alcohol. For men who are not looking to quit alcohol, it is recommended that you take these supplements after consuming alcohol to inhibit its harmful effects.

Note that alcohol detox supplements are designed to support the body's recovery. They cannot substitute abstinence, a healthy diet, or regular exercise. If you are taking prescription medications, you should also speak to your doctor about supplements for liver repair from alcohol to ensure you do not experience any adverse side effects.

What is Acetaldehyde?

Acetaldehyde is the by-product of the body's metabolic processes when it comes into contact with alcohol. Whenever you drink any amount of alcohol, your body will help metabolize it, but the side effect of this process is the formation of acetaldehyde.

Acetaldehyde is a toxic substance for your body because it causes direct damage to DNA in your cells. Your DNA is the instruction manual for normal growth and function. Cells can experience uncontrolled division whenever their DNA becomes damaged, which may result in cancerous tumors.

Your cancer risk increases whenever the human body experiences a toxic buildup of this substance. According to the CDC, at least six cancers have been linked to alcohol use, including mouth and throat, rectum, breast, and liver cancer.

In short, your body needs help to metabolize alcohol and detoxify itself to protect vital organs, especially the liver. Taking a supplement for alcohol detox is beneficial because of the targeted ingredients inside.

Side Effects of Alcohol Detox Capsules

An alcohol metabolism supplement is beneficial for supporting your body in combating the dangerous effects of alcohol consumption. However, you need to educate yourself on the potential for side effects.

All supplements have the potential to cause side effects in large doses, and an anti-alcohol supplement is no exception. However, side effects have been noted to be mild and non-life-threatening.

Do your research by reading through scientific studies and examining the anecdotal evidence from people who have already taken a supplement for alcohol detox. Being aware of alcohol detox side effects is part of being an informed supplement user.

Note that most instances of alcohol detox side effects occur due to people purchasing poor-quality supplements from untrustworthy vendors or exceeding the recommended daily dosage.

If you experience any side effects from taking natural alcohol detox supplements, stop taking these supplements and consult your doctor.

Why is Buying Anti-Alcohol Supplements from Supersmart the Best Choice?

Taking a liver protection supplement is the smart choice for people who are concerned about the effects of alcohol on their body.

At Supersmart, we are one of the leading names in the industry because of our uncompromising approach to inspecting supplements and ensuring we only sell products with proven benefits. Our supplements have been independently tested and certified for efficacy and safety by independent laboratories.

We take pride in giving our customers the peace of mind of knowing they are choosing a well-respected company within the supplements industry. Check out our reviews to find out what our previous customers think of our services.

1. Šalamon Š, Kramar B, Marolt TP, Poljšak B, Milisav I. Medical and Dietary Uses of N-Acetylcysteine. Antioxidants (Basel). 2019;8(5):111. Published 2019 Apr 28. doi:10.3390/antiox8050111
2. Vasdev S, Mian T, Longerich L, Prabhakaran V, Parai S. N-acetyl cysteine attenuates ethanol induced hypertension in rats. Artery. 1995;21(6):312-6. PMID: 8833231.
3. Lim DJ, Sharma Y, Thompson CH. Vitamin C and alcohol: a call to action. BMJ Nutr Prev Health. 2018;1(1):17-22. Published 2018 Dec 5. doi:10.1136/bmjnph-2018-000010
4. Pirlich M, Kiok K, Sandig G, Lochs H, Grune T. Alpha-lipoic acid prevents ethanol-induced protein oxidation in mouse hippocampal HT22 cells. Neurosci Lett. 2002 Aug 9;328(2):93-6. doi: 10.1016/s0304-3940(02)00415-9. PMID: 12133563.
5. Langlais PJ. Alcohol-Related Thiamine Deficiency: Impact on Cognitive and Memory Functioning. Alcohol Health Res World. 1995;19(2):113-121.
6. Manzardo AM, He J, Poje A, Penick EC, Campbell J, Butler MG. Double-blind, randomized placebo-controlled clinical trial of benfotiamine for severe alcohol dependence. Drug Alcohol Depend. 2013;133(2):562-570. doi:10.1016/j.drugalcdep.2013.07.035
7. Kärkkäinen O, Klåvus A, Voutilainen A, Virtanen J, Lehtonen M, Auriola S, Kauhanen J, Rysä J. Changes in Circulating Metabolome Precede Alcohol-Related Diseases in Middle-Aged Men: A Prospective Population-Based Study With a 30-Year Follow-Up. Alcohol Clin Exp Res. 2020 Dec;44(12):2457-2467. doi: 10.1111/acer.14485. Epub 2020 Nov 2. PMID: 33067815.
8. Gillessen A, Schmidt HH. Silymarin as Supportive Treatment in Liver Diseases: A Narrative Review. Adv Ther. 2020;37(4):1279-1301. doi:10.1007/s12325-020-01251-y
9. Rastogi R, Saksena S, Garg NK, Kapoor NK, Agarwal DP, Dhawan BN. Picroliv protects against alcohol-induced chronic hepatotoxicity in rats. Planta Med. 1996 Jun;62(3):283-5. doi: 10.1055/s-2006-957882. PMID: 8693047.
10. Penetar DM, Toto LH, Lee DY, Lukas SE. A single dose of kudzu extract reduces alcohol consumption in a binge drinking paradigm. Drug Alcohol Depend. 2015;153:194-200. doi:10.1016/j.drugalcdep.2015.05.025
11. Swift R, Davidson D. Alcohol hangover: mechanisms and mediators. Alcohol Health Res World. 1998;22(1):54-60.
12. Patel R, Mueller M. Alcoholic Liver Disease. [Updated 2022 Jan 19]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK546632/
13. Lieber CS. Metabolic effects of acetaldehyde. Biochem Soc Trans. 1988 Jun;16(3):241-7. doi: 10.1042/bst0160241. PMID: 3181606.
14. Nutt D, Hayes A, Fonville L, et al. Alcohol and the Brain. Nutrients. 2021;13(11):3938. Published 2021 Nov 4. doi:10.3390/nu13113938
15. Hoyumpa AM. Mechanisms of vitamin deficiencies in alcoholism. Alcohol Clin Exp Res. 1986 Dec;10(6):573-81. doi: 10.1111/j.1530-0277.1986.tb05147.x. PMID: 3544907.
16. Madeira MD, Sousa N, Lieberman AR, Paula-Barbosa MM. Effects of chronic alcohol consumption and of dehydration on the supraoptic nucleus of adult male and female rats. Neuroscience. 1993 Oct;56(3):657-72. doi: 10.1016/0306-4522(93)90363-k. PMID: 8255426.
17. Prescott LF. Paracetamol, alcohol and the liver. Br J Clin Pharmacol. 2000;49(4):291-301. doi:10.1046/j.1365-2125.2000.00167.x
18. Mofredj A, Cadranel JF, Darchy B, Barbare JC, Cazier A, Pras V, Biour M. Toxicité hépatique du paracétamol à dose thérapeutique chez le sujet éthylique chronique. A propos de 2 cas d'hépatite mortelle chez des patients cirrhotiques [Hepatotoxicity caused by therapeutic doses of paracetamol in alcoholics. Report of 2 cases of fatal hepatitis in cirrhosis]. Ann Med Interne (Paris). 1999 Oct;150(6):507-11. French. PMID: 10615538.
19. Shi, Peiying et al. “Honey reduces blood alcohol concentration but not affects the level of serum MDA and GSH-Px activity in intoxicated male mice models.” BMC complementary and alternative medicine vol. 15 225. 14 Jul. 2015, doi:10.1186/s12906-015-0766-5
20. Shen Y, Lindemeyer AK, Gonzalez C, et al. Dihydromyricetin as a novel anti-alcohol intoxication medication. J Neurosci. 2012;32(1):390-401. doi:10.1523/JNEUROSCI.4639-11.2012