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Welcome Shop by health concern Stress & Mood Peptidea®
Peptidea®
Peptidea®
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Peptidea®
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$29.00 In Stock
Description

Peptidea® is a fish protein hydrolysate that plays a regulatory role in the nervous system.

  • Helps reduce muscle and mental fatigue, insomnia, and depression.
  • Boosts memory and cognitive function.
  • Effective at reducing anxiety.
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Peptidea Supplement

Peptidea® is a fish protein hydrolysate supplement, in vegetarian capsules. It consists of peptides and 18 amino acids with a molecular weight lower than 1,000 daltons. They acts as precursors of endorphins and other neurotransmitters such as serotonin and melatonin, which play a regulatory role in the nervous system.

They therefore help the body adapt effectively to physical or mental stress. You can now buy this supplement in SuperSmart's online catalogue.

How does the Body React to Stress?

In response to stress, danger, or emotion, the body initiates two mechanisms:

  1. First, the adrenal gland releases adrenalin and other catecholamines to prepare the body to react by rapidly providing the brain and muscles with maximum energy.
  2. Then, it is the turn of the pituitary gland and adrenal cortex. The hypothalamus secretes a hormone, CRF (corticotrophin-releasing factor) which stimulates the pituitary gland. The latter releases ACTH into the blood which is essential for the secretion of corticosteroids (cortisone, cortisol) by the adrenal cortex.

Cortisol, often called the 'stress hormone', is known to have a blood sugar-elevating effect. At high levels, it stimulates protein catabolism (formation of amino acids). During prolonged periods of stress, high levels of cortisol are secreted, potentially damaging the limbic system involved in emotion, as well as weakening immune defenses.

What are the Effects of Peptidea® on Stress?

Trials conducted on rats show that, under conditions of stress, Peptidea® helped reduce the intensity of ACTH secretion. Besides, in animals treated with Peptidea®, the rate of transport of adrenalin and noradrenalin was slower. Finally, a change in GABA levels (gamma amino-butyric acid) in the brain was observed, similar to that resulting from an injection of benzodiazepine.

Compared with benzodiazepines, orally-administered capsules of the fish peptides in Peptidea® showed a clear anti-stress effect in adult Wistar rats. Unlike benzodiazepines, Peptidea® produced this anti-stress action without any sedative effect, the animals maintaining all their adaptive capacity.

Previous studies had shown that fish protein hydrolysates has several benefits, including:

  • Effective at reducing anxiety in a healthy student population, the benefits appearing within a week of starting treatment.
  • Reduced muscle and mental fatigue, anxiety, insomnia, depression in 65% of subjects suffering from asthenia and severe anxiety, after just two weeks' treatment.
  • Had beneficial effects in cases of cognitive and memory problems, with improvements observed in the quality of sleep, motivation, concentration and memorization; their beneficial effect on depression-related fatigue and weakness may explain the improvements in memory and cognitive function.
  • Led to improved learning as a result of reducing anxiety.
  • Provided beneficial effects on stress which remained for a while even after treatment ceased.
  • Offered effective relief from symptoms of fatigue, anxiety and depression caused by chronic stress.

Buy your Peptidea® anti-stress supplement today.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Composition
Daily serving: 6 capsules
Number of servings per bottle: 15
Quantity per serving
Peptidyss® 1,200 mg
Other ingredient: acacia gum.
Peptidyss® - Abyss Ingredients, France.

Each vegetarian capsule contains 200 mg of Peptidyss®.
Directions for use

Adults: Take between 1 and 6 capsules every morning for at least 15 consecutive days.

Warning: do not take Peptidea if allergic to fish.

Precautions: do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used as a substitute for a varied, balanced diet or a healthy lifestyle. Keep out of children’s reach. Store away from light, heat, and humidity. As with any nutritional supplement, consult a health care practitioner before use if you are pregnant, breastfeeding, or have a medical condition.

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Reviews 1
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Stacy B
5
Helps with mood and energy, I bought a bunch when the price dropped temporarily so I was able to take the full daily recommended dose for a few weeks. It's expensive at 15 daily services per bottle.
References
  1. Hepsomali P, Groeger JA, Nishihira J, Scholey A. Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review. Front Neurosci. 2020;14:923. Published 2020 Sep 17. doi:10.3389/fnins.2020.00923
  2. Jewett BE, Sharma S. Physiology, GABA. [Updated 2021 Jul 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK513311/
  3. Sprouse-Blum AS, Smith G, Sugai D, Parsa FD. Understanding endorphins and their importance in pain management. Hawaii Med J. 2010;69(3):70-71.
  4. Pilozzi A, Carro C, Huang X. Roles of β-Endorphin in Stress, Behavior, Neu-roinflammation, and Brain Energy Metabolism. Int J Mol Sci. 2020;22(1):338. Published 2020 Dec 30. doi:10.3390/ijms22010338
  5. Klasen M, Wolf D, Eisner PD, et al. Serotonergic Contributions to Human Brain Aggression Networks. Front Neurosci. 2019;13:42. Published 2019 Feb 22. doi:10.3389/fnins.2019.00042
  6. Xie Z, Chen F, Li WA, Geng X, Li C, Meng X, Feng Y, Liu W, Yu F. A review of sleep disorders and melatonin. Neurol Res. 2017 Jun;39(6):559-565. doi: 10.1080/01616412.2017.1315864. Epub 2017 May 1. PMID: 28460563.
  7. Chataigner M, Lucas C, Di Miceli M, et al. Dietary Fish Hydrolysate Improves Memory Performance Through Microglial Signature Remodeling During Aging. Front Nutr. 2021;8:750292. Published 2021 Nov 23. doi:10.3389/fnut.2021.750292
  8. McCraty R, Zayas MA. Cardiac coherence, self-regulation, autonomic stability, and psychosocial well-being. Front Psychol. 2014;5:1090. Published 2014 Sep 29. doi:10.3389/fpsyg.2014.01090
  9. Goldfarb AH, Jamurtas AZ. Beta-endorphin response to exercise. An update. Sports Med. 1997 Jul;24(1):8-16. doi: 10.2165/00007256-199724010-00002. PMID: 9257407.
  10. Hulsken S, Märtin A, Mohajeri MH, Homberg JR. Food-derived seroto-nergic modulators: effects on mood and cognition. Nutr Res Rev. 2013 Dec;26(2):223-34. doi: 10.1017/S0954422413000164. Epub 2013 Oct 18. PMID: 24134856.
  11. Nehlig A. The neuroprotective effects of cocoa flavanol and its in-fluence on cognitive performance. Br J Clin Pharmacol. 2013;75(3):716-727. doi:10.1111/j.1365-2125.2012.04378.x
  12. Dfarhud D, Malmir M, Khanahmadi M. Happiness & Health: The Biolo-gical Factors- Systematic Review Article. Iran J Public Health. 2014;43(11):1468-1477.
  13. Choi DW, Chun SY, Lee SA, Han KT, Park EC. Association between Sleep Duration and Perceived Stress: Salaried Worker in Circumstances of High Workload. Int J Environ Res Public Health. 2018;15(4):796. Published 2018 Apr 19. doi:10.3390/ijerph15040796
  14. Hidese S, Ogawa S, Ota M, et al. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients. 2019;11(10):2362. Published 2019 Oct 3. doi:10.3390/nu11102362
  15. Jamshidi N, Cohen MM. The Clinical Efficacy and Safety of Tulsi in Humans: A Systematic Review of the Literature. Evid Based Complement Al-ternat Med. 2017;2017:9217567. doi:10.1155/2017/9217567
  16. Pickering G, Mazur A, Trousselard M, et al. Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients. 2020;12(12):3672. Published 2020 Nov 28. doi:10.3390/nu12123672

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