Paradoxine® – Grains of Paradise Supplement

What are Grains of Paradise?

The Aframomum melegueta plant, source of the grains of paradise spice, comes from the Zingiberaceae plant family, also known as the ginger family. The plant pods contain red-brown seeds. Often used in cooking, these seeds provide a peppery and spicy flavor. Grains of paradise are also known by other names, such as alligator pepper, melegueta pepper, Guinea grains, efom wisa, and ossame.

Several compounds inside these seeds create their pungent flavor and aroma. However, the compounds may also aid in burning fat. These powerful compounds include 6-paradol, 6-shogaol, 6-gingerdione, and 6-gingerol. Of these, the most vital compounds offering benefits to your health include 6-paradol and 6-gingerol, with 6-gingerol also found in ginger.

Why would someone consider taking grains of paradise from Paradoxine® pills? To answer that question, let's look at some of the top grains of paradise extract benefits and most common Paradoxine® uses.

Grains of Paradise Benefits

Also known as melegueta pepper or alligator pepper, grains of paradise is a perennial plant that, like ginger, belongs to the Zingiberaceae family. Native to West Africa, it is widely used both for its digestive benefits and aphrodisiac properties.

The beneficial effects of Aframomum melegueta are primarily linked to the presence of an active phenol compound called 6-paradol in this supplement. This compound is also responsible for the plant's spicy taste, similar to ginger. The chemical structure of 6-paradol is close to that of some of the compounds found in ginger, such as zingerone, 6-gingerol, and 6-shogaol.

What about Paradoxine® for weight loss? There are a number of top-performing plants with fat-burning effects. However, grains of paradise are often chosen over others because of their efficacy at reducing adipose tissue and their absence of unwelcome side-effects. Other natural fat-burners contain substances like caffeine, to which some people are sensitive and, in some cases, can have a negative effect on the central nervous system.

Many people consider weight loss among the top grains of paradise benefits. But what do studies show about Paradoxine® benefits and can you count on grains of paradise for fat loss results?

What do Studies Show About Grains of Paradise Supplementation?

The grains of paradise health benefits have been the subject of numerous scientific studies:

• Studies show that supplementing with this plant extract may not only constitute a gentle way of fighting the accumulation of fat but may also attack existing body fat reserves.
• Scientists attribute these benefits to the presence of 6-paradol, as it may trigger thermogenesis of brown fat tissue, which, in turn, stimulates weight loss.
• Along with its potential slimming effects, an extract of grains of paradise offers other health benefits. For example, it is recognized as an effective stimulant.
• Some scientists believe it has greater aphrodisiac activity than Piper guineense, which is used to treat erectile problems.
• Other studies have looked at the mechanisms of action of 6-paradol. According to such research, it may help combat glycation processes and have an anti-tumor effect.

These are just some of the health benefits of grains of paradise that have been studied. With more studies, we may uncover more grains of paradise extract uses.

How to Take Paradoxine®?

Paradoxine® is formulated from an extract of grains of paradise standardized to 12.5% of 6-paradol. We recommend adults to take 3 capsules of 40 mg a day, which is equivalent to an optimal daily intake of 120 mg of Paradoxine®. This dose can be adjusted but only if advised by a healthcare professional.

We recommend taking one capsule after each meal. If you take three pills each day, the container will last a month. As of now, there is no research indicating the safe maximum Paradoxine® dose. If you want to find the ideal Paradoxine® dosage for your situation, it is best to speak with a healthcare provider.

Before you take Paradoxine® pills or any dietary supplement, you should always discuss your healthcare needs with a professional. And while there are no major Paradoxine® side effects to be aware of, you should never start taking grains of paradise supplements without professional guidance, especially if you take other medications or have underlying health conditions.

We suggest that you research the grains of paradise side effects before taking our supplement. Aside from any grains of paradise extract side effects you find, it is also not recommended to take this supplement if you are pregnant or breastfeeding due to a lack of research. Until more studies are performed, we suggest avoiding our supplement if you are an expecting or nursing mother.

Buy Paradoxine® and combine it with a healthy diet and exercise for the best results.

1. Sugita J, Yoneshiro T, Sugishima Y, et al. Daily ingestion of grains of paradise (Aframomum melegueta) extract increases whole-body energy expenditure and decreases visceral fat in humans. J Nutr Sci Vitaminol (Tokyo). 2014;60(1):22-27. doi:10.3177/jnsv.60.22
2. Iwami M, Mahmoud FA, Shiina T, et al. Extract of grains of paradise and its active principle 6-paradol trigger thermogenesis of brown adipose tissue in rats. Auton Neurosci. 2011;161(1-2):63-67. doi:10.1016/j.autneu.2010.11.012
3. Sugita J, Yoneshiro T, Hatano T, et al. Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men. Br J Nutr. 2013;110(4):733-738. doi:10.1017/S0007114512005715
4. Kamtchouing P, Mbongue GY, Dimo T, Watcho P, Jatsa HB, Sokeng SD. Effects of Aframomum melegueta and Piper guineense on sexual behaviour of male rats. Behav Pharmacol. 2002;13(3):243-247. doi:10.1097/00008877-200205000-00008
5. Wei CK, Tsai YH, Korinek M, et al. 6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice. Int J Mol Sci. 2017;18(1):168. Published 2017 Jan 17. doi:10.3390/ijms18010168