Paradoxine® is a standardized extract of grains of paradise (Aframomum melegueta), a spice from the ginger family that seems to have been traditionally used in West Africa.*
This supplement provides 12.5% 6-paradol, a naturally occurring phenolic compound believed to help activate brown fat and promote metabolic activity.*
Potential Benefits of Grains of Paradise*
Also known as melegueta pepper or alligator pepper, grains of paradise is a perennial plant from the Zingiberaceae family – like ginger.* Native to West Africa, it seems to have been traditionally valued for its culinary and botanical uses.* One of its standout compounds, 6-paradol, is a naturally occurring phenol responsible for its distinct spicy flavor.*
6-paradol appears to share structural similarities with well-known ginger constituents such as zingerone, 6-gingerol, and 6-shogaol.* This compound may play a key role in supporting metabolic activity and fat oxidation, potentially making grains of paradise a popular option in wellness formulas aimed at body composition support.*
Compared to other botanicals that might be used for fat metabolism – such as caffeine-based ingredients or chili-derived capsaicin –, grains of paradise seems appreciated for offering a stimulant-free approach.* It may be commonly chosen by those looking for a gentler alternative that may help the body manage energy expenditure without impacting the nervous system.*
To summarize, a grains of paradise supplement may:*
- Help stimulate thermogenesis in brown adipose tissue, potentially supporting calorie expenditure.*
- Contribute to body composition efforts when combined with healthy lifestyle choices.*
- Offer a caffeine-free approach for those seeking metabolic support without common stimulants.*
Grains of Paradise Supplementation and Scientific Research*
The potential weight management benefits of grains of paradise appear to have been explored in a variety of scientific studies:*
- Some studies might suggest that 6-paradol may help encourage fat metabolism and reduce body fat stores when taken consistently.*
- Grains of paradise extract may have been shown to increase energy expenditure by activating brown fat tissue in clinical trials.*
- Animal and in vitro studies seem to show promising effects on fat oxidation pathways.*
Paradoxine® is delivered in vegetarian capsules and formulated without stimulants.* Each daily dose of 3 capsules provides 15 mg of 6-paradol.* This dose may be personalized based on your individual needs under the guidance of a qualified healthcare professional.*
WARNINGS
Do not exceed the recommended daily dose. This product is a nutritional supplement and should not be used as a substitute for a varied and balanced diet or a healthy lifestyle.
STORAGE
Store in a cool, dry place away from direct sunlight, heat, and humidity.
Keep out of reach of children.
PREGNANCY AND MEDICAL CONDITIONS
If you are pregnant, breastfeeding, or have any medical conditions, consult your healthcare provider before using this product.
SUPPLEMENT INTERACTIONS
Consult your healthcare provider before use, especially if you are taking any medications or other supplements as there may be potential interactions.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Serving size: 3 capsules
Servings per container: 30 |
Amount per serving |
Paradoxine® Extract of Grains of Paradise standardized to 12.5% 6-Paradol |
120 mg |
Other Ingredients: vegetable capsule (hypromellose), acacia gum, white rice flour.
Paradoxine® is a registered trademark of Suzhou Win Health International Co., Ltd.
|
Take 3 vegetarian capsules a day, one after each meal.
Each vegetarian capsule contains 40 mg of Paradoxine®.
30 days.
Store in a cool, dark, and dry place.
As with all nutritional supplements, consult a health professional before taking this supplement. Not recommended for pregnant or breastfeeding women or those with a potential health concern.*
For adults only. Do not exceed the recommended daily dose. This product is a dietary supplement and should not be used as a substitute for a varied, balanced diet and a healthy lifestyle. Keep out of children’s reach.
- Sugita J, Yoneshiro T, Sugishima Y, et al. Daily ingestion of grains of paradise (Aframomum melegueta) extract …. J Nutr Sci Vitaminol (Tokyo). 2014;60(1):22-27. doi:10.3177/jnsv.60.22
- Iwami M, Mahmoud FA, Shiina T, et al. Extract of grains of paradise and its active principle 6-paradol …. Auton Neurosci. 2011;161(1-2):63-67. doi:10.1016/j.autneu.2010.11.012
- Sugita J, Yoneshiro T, Hatano T, et al. Grains of paradise (Aframomum melegueta) extract …. Br J Nutr. 2013;110(4):733-738. doi:10.1017/S0007114512005715
- Kamtchouing P, Mbongue GY, Dimo T, Watcho P, Jatsa HB, Sokeng SD. Effects of Aframomum melegueta and Piper guineense …. Behav Pharmacol. 2002;13(3):243-247. doi:10.1097/00008877-200205000-00008
- Wei CK, Tsai YH, Korinek M, et al. 6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, …. Int J Mol Sci. 2017;18(1):168. Published 2017 Jan 17. doi:10.3390/ijms18010168