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L-OptiZinc® Supplement
L-OptiZinc® Supplement
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Sans nano-particulesSans glutenVegan
Tiredness and Lack of energy
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L-OptiZinc® is a zinc supplement with high bioavailability.

  • Has great antioxidant potency, offering effective cell protection against free radical attack.
  • Essential for the development and activation of T-lymphocytes - white blood cells that fight infection.
  • Reduces incidence of respiratory infections.
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Wooden cubes with the letter's 'Z' and 'N', representing zinc


What is L-OptiZinc®? It is a unique, patented form of methionine-bound zinc, the amino acid best absorbed by the body. Studies show that Supersmart’s L-OptiZinc® formula is better absorbed, retained longer and is more effective than any other zinc supplement available.

In contrast to other zinc supplements, the bioavailability of the zinc is not affected by the type of food or amount of fiber consumed. It also has greater antioxidant potency, equivalent to Vitamins E, C and beta-carotene, offering several benefits and effective cell protection against free radical attack.

On this page, we discuss all the L-OptiZinc health benefits, discuss the importance of bioavailability and look at the side effects associated with this vital supplement.

What are the health benefits of L-OptiZinc®?

Zinc is a trace element essential to a number of vital cell functions, including growth, development, reproduction and digestion, as well as cerebral, nervous, immune and visual functions.

Zinc is required for the catalytic activity of more than 100 enzymes in the body. It also supports development and growth during pregnancy, childhood and adolescence.

Considering the body doesn’t have a specialized zinc storage system, it’s essential that you receive the daily recommended amount of this mineral through your food intake or supplements.

The Office of Dietary Supplements states that zinc has several health benefits, including the following:

  • Promotes adequate immune function
  • Aids in wound healing
  • May shorten the duration and intensity of diarrhea
  • Could reduce the severity and duration of the common cold
  • Could delay the progression of age-related macular degeneration and vision loss

Extensive studies have been done related to specific zinc health benefits and side effects. Keep reading to learn about how zinc benefits t-lymphocytes, why it has high bioavailability and why there are so few side effects of L-OptiZinc® compared with other supplements.

It Helps Activate T-Lymphocytes

The best form of zinc — methionine-bound zinc — has been studied to play a very important role in the function of the immune system. It is essential for the development and activation of T-lymphocytes — white blood cells that fight infections. In humans, zinc deficiency results in a decrease in T lymphocytes, which hinder the body’s ability to combat infections and heal wounds.

Because of the effect zinc has on immune support, the following benefits can also be found:

  • Methionine-bound zinc, which is found in Opti L Zinc 30 mg, is an essential component of zinc/copper superoxide dismutase, an important antioxidant enzyme, capable of neutralizing harmful superoxide radicals. Maintaining proper levels of superoxide dismutases (SOD) and zinc is key to longevity, as aging is associated with damage caused by reactive oxygen species.
  • Methionine-bound zinc may also ease symptoms and reduce the duration of the common cold, according to some studies.
  • According to WHO, zinc supplements could reduce the incidence of respiratory infections, such as the cold and flu. It may also reduce the generation of inflammatory cells and markers of oxidative stress.
  • Research indicates that zinc halves the risk of developing pneumonia in elderly people in nursing homes, plus also reduces antibiotic treatment times and convalescence periods.
  • Other studies show that zinc can regulate cyclo-oxygenase-2 (COX-2), an enzyme involved in inflammation and pain as well as in the development of certain cancers. A study on an animal model showed that zinc deficiency encouraged tumor growth and an excess of COX-2, while supplementation reduced levels of the latter and incidence of tumors.
  • Zinc is also proven to be an essential mineral for growth and maturation. Deficiency is linked with cognitive deficits and delayed growth, including a delay in male and female puberty.

Combined, these health benefits provide a boost to overall health and general well-being.

It Has High Bioavailability

When you want a fast-acting supplement, you look at its bioavailability. This term describes the absorption of a drug or supplement into systemic circulation. What it really comes down to is, some forms of zinc take longer to work within the human body than others.

However, methionine-bound zinc is often the best form of a zinc supplement if you’re looking for maximum bioavailability. Studies show the zinc bioavailability of this form is faster than other variants.

But there are other factors that can hinder zinc bioavailability:

  • Digestive disorders: Conditions such as irritable bowel syndrome, Crohn’s, celiac disease and chronic heartburn can impact the body’s ability to absorb nutrients.
  • Alcohol: This substance promotes the breakdown of pills quickly before they reach the small intestine, where the majority of absorption occurs. It can also damage the stomach lining, which reduces the absorption of minerals.
  • Caffeine: Just like with alcohol, caffeine reduces nutrient absorption, but it also promotes excretion of minerals.
  • Stress: Being under constant stress puts your body under a lot of pressure. Your systems go into “fight or flight” mode, which hits the digestive system and affects how you absorb nutrients.

If you want zinc supplements with high bioavailability, you’ll want to choose a high-quality product.

L-OptiZinc Side Effects Are Uncommon

Fortunately, there are very few L-OptiZinc side effects recognized, and taking this supplement is considered relatively safe. According to the Office of Dietary Supplements, zinc toxicity is a rare occurrence. In fact, it’s perfectly safe to take 40 mg or less of zinc each day.

However, if you currently take antibiotics, you may want to speak with your healthcare provider before starting a zinc regimen. Some supplements can interact with antibiotics, and that may reduce the effectiveness, especially if taken at the same time.

In some instances, toxicity can occur if too much zinc is consumed. The symptoms of high zinc intake include a loss of appetite, vomiting, nausea, diarrhea, headaches and abdominal cramps. Taking too much zinc can also cause the body to be low in copper, reduce immune system function, alter the body’s iron function and cause a reduction in high-density lipoproteins.

Another commonly cited side effect of zinc supplements is digestive issues. However, the impact of zinc on digestion correlates with bioavailability. And with the L-OptiZinc® supplement, you receive methionine-bound zinc, which has a high absorption rate and limits the impact on digestion.

Daily serving: 1 tablet
Number of servings per bottle : 120

per serving

L-OptiZinc® (providing 30 mg elemental zinc) 150 mg
Other ingredients: calcium carbonate, stearic acid, maltodextrin, croscarmellose sodium, shellac.
Directions for use

L-OptiZinc® Supplement Dosage

One L-OptiZinc® tablet contains 150mg of methionine-bound zinc complex, which equates to 30mg of elemental zinc, leaving you under the upper intake recommended for daily usage. At this dosage, you should not experience any negative side effects. Taking zinc supplements with food increases the absorption rate because the nutrients can work together. However, taking zinc with iron, copper or phosphorus supplements can inhibit absorption. Zinc supplements should be taken on their own. By storing your supplements in a cool, dry area, you further promote bioavailability. Keep the supplement away from heat, humidity and direct sunlight to maintain maximum potency.

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  1. Hönscheid A, Rink L, Haase H. T-lymphocytes: a target for stimulatory and inhibitory effects of zinc ions. Endocr Metab Immune Disord Drug Targets. 2009;9(2):132-144. doi:10.2174/187153009788452390
  2. Hojyo S, Fukada T. Roles of Zinc Signaling in the Immune System. J Immunol Res. 2016;2016:6762343. doi:10.1155/2016/6762343
  3. Meydani SN, Barnett JB, Dallal GE, et al. Serum zinc and pneumonia in nursing home elderly [published correction appears in Am J Clin Nutr. 2008 Apr;87(4):1071]. Am J Clin Nutr. 2007;86(4):1167-1173. doi:10.1093/ajcn/86.4.1167
  4. Fong LY, Zhang L, Jiang Y, Farber JL. Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats. J Natl Cancer Inst. 2005;97(1):40-50. doi:10.1093/jnci/dji006
  5. Dhawan DK, Chadha VD. Zinc: a promising agent in dietary chemoprevention of cancer. Indian J Med Res. 2010;132(6):676-682.
  6. Rerksuppaphol S, Rerksuppaphol L. Zinc supplementation enhances linear growth in school-aged children: A randomized controlled trial. Pediatr Rep. 2018;9(4):7294. Published 2018 Jan 4. doi:10.4081/pr.2017.7294
  7. Sauer AK, Pfaender S, Hagmeyer S, et al. Characterization of zinc amino acid complexes for zinc delivery in vitro using Caco-2 cells and enterocytes from hiPSC. Biometals. 2017;30(5):643-661. doi:10.1007/s10534-017-0033-y

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