Arginine Alpha Ketoglutarate (AKG) Supplement

This AKG supplement has been developed from a very specific form of arginine called L-arginine alpha ketoglutarate, a combination of alpha-ketoglutarate acid and arginine.

What is arginine alpha ketoglutarate? Essential for the healthy functioning of the human body, arginine is an amino acid involved in many of the body's metabolic processes.

With a role in the synthesis of numerous molecules, such as creatine, nitric oxide and human growth hormone, this amino acid offers a number of benefits. Scientists believe it has positive effects on the immune system, the cardiovascular system, and muscles.

Arginine Alpha Ketoglutarate Benefits

By providing an intake of L-arginine, arginine alpha ketoglutarate supplements promote the production of nitric oxide, a compound known for its essential role in the vascular system, which indirectly supports libido. Studies show AKG may support muscle growth as well.

Below are details related to the most commonly recognized L-arginine alpha ketoglutarate benefits.

Vasodilatory Properties

Increased nitric oxide production causes the blood vessels to dilate as the muscles in the vessel walls relax. This vasodilatory effect works to inhibit an increase in blood pressure.

This specific form of arginine has been shown in recent research to be particularly effective in supporting cardiovascular health, as it promotes quicker and longer-lasting nitric oxide production.

Increases Libido

As a result of its vasodilatory properties, arginine has demonstrated positive effects on libido in recent studies. By promoting nitric oxide production, arginine improves blood flow in every region of the body, including the genitals. It is also known to increase the production of growth hormone, which is involved in both male and female reproductive processes. Supplementing with arginine, in the form of AKG, may therefore help increase libido and response to sexual stimuli. Improvements in sexual desire, in particular, have been observed in people supplemented with arginine alpha ketoglutarate.

Supports Muscle Growth

Weight-lifting enthusiasts should look into L-arginine alpha ketoglutarate for bodybuilding. Taking AKG supplements for bodybuilding has been widely studied. In fact, for some years now, AKG workout supplements have been very popular with fitness enthusiasts, particularly weight lifters. This is because of arginine's stimulating effect on the production of growth hormone, which burns fat and produces cellular energy. The relationship between arginine and growth hormone indicates arginine supports muscle activity.

AKG Supplement Side Effects

Whether you’re interested in taking arginine alpha ketoglutarate for bodybuilding or you just want the best AKG supplement, it's important you research potential side effects before you start a new regimen. While arginine alpha ketoglutarate side effects are minimal, adverse reactions are still possible.

We recommend discussing the potential L-arginine Alpha Ketoglutarate side effects with your doctor to determine if taking AKG is right for you. Be sure to discuss any existing health conditions you have, as well any medications and supplements you’re currently taking to rule out negative interactions.

Often, the benefits of taking AKG supplements will outweigh the risks, but this is something only your physician can determine. Additionally, if adverse reactions should occur after taking a new supplement, it's important that you discontinue taking it immediately. Once your doctor has determined that the new supplement isn't to blame, you will be able to begin the supplementation once again.

This supplement is only intended to boost your overall well-being. It's not meant to heal or treat any disease or ailment. This supplement is designed for healthy adults; it is not recommended for children. More research is needed to determine the safety of AKG during pregnancy or while breastfeeding.

If you are pregnant or breastfeeding, we recommend avoiding this supplement until more arginine alpha ketoglutarate studies are available that confirms it’s safe to take.

How To Take Arginine Alpha Ketoglutarate Supplements

The nutritional supplement Arginine Alpha Ketoglurarate provides an optimal level of 1000 mg of AKG per capsule. We recommend taking between 3 and 12 capsules a day, depending on your needs.If you’re unsure of how much to take, you should seek advice from your doctor.

There are several other arginine supplements within the Supersmart catalog, including L-Citrulline, a natural arginine precursor, and the complex Acetyl L Carnitine Arginate, which combines arginine and carnitine, another amino acid involved in cellular energy production.

If you end up taking 12 tablets a day, one bottle will provide a total of eight servings. The only other ingredients included in this formulation include acacia gum, ensuring you only consume what is needed. You won't find unnecessary fillers and ingredients in any Supersmart formulas.

When you first start taking an AKG supplement, you may want to limit the number of capsules you take. It will give you time to adjust to the new formulation and help you determine if you will experience any side effects. You can gradually take more capsules until you reach the optimal amount for your needs.

We recommend storing all supplements in a climate-controlled and dry environment, outside of direct sunlight, and away from children and pets. Many people store their supplements in a medicine cabinet. When stored correctly, supplements should maintain potency through the best-by date. Once this date passes, it's time to dispose properly of the supplements and invest in a new bottle.

We also recommend re-evaluating AKG supplementation, from time to time. As your lifestyle changes and you age, you may want to adjust the number of capsules you take to fit your changing health needs. If you are ever unsure what's right for you, please seek the advice of your doctor.

1. Willoughby DS, Boucher T, Reid J, Skelton G, Clark M. Effects of 7 days of arginine-alpha-ketoglutarate supplementation on blood flow, plasma L-arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise. Int J Sport Nutr Exerc Metab. 2011;21(4):291-299.
2. Cieri-Hutcherson NE, Jaenecke A, Bahia A, et al. Systematic Review of l-Arginine for the Treatment of Hypoactive Sexual Desire Disorder and Related Conditions in Women. Pharmacy (Basel). 2021;9(2):71. Published 2021 Mar 27. doi:10.3390/pharmacy9020071
3. Stefani GP, Marmett B, Alves JP, et al. Resistance training and L-arginine supplementation are determinants in genomic stability, cardiac contractility and muscle mass development in rats. PLoS One. 2018;13(9):e0204858. Published 2018 Sep 27. doi:10.1371/journal.pone.0204858