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Wild Amazonian Formula Supplement
Wild Amazonian Formula Supplement
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Wild Amazonian Formula
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Wild Amazonian Formula is an exceptional formula from the Amazon that develops the body’s natural ability to self-heal

  • Unique formulation inspired by the natural pharmacopoeia of indigenous Amazonian people
  • Hand-picked and extracted from five revered and scientifically-documented medicinal plants from the Amazon: suma root, cat’s claw, graviola, lapacho bark and mullaca
  • Helps stimulate the immune system against exogenous and endogenous attacks
  • Supports healthy cells in fighting oxidants and tracking down abnormal cells
  • Helps the body repair errors and mutations to DNA
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120 Veg. Caps
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Amazon rainforest in a sunset light

Wild Amazonian Formula - Rainforest Herbal Supplements

The Wild Amazonian Formula is a clever mix of five wild plants from the Amazon designed to stimulate the immune system and support the body's ability to self-heal. Each of these medicinal plants has been carefully selected for its immune-stimulant and anti-proliferative properties. They are all hand-picked from the open-air botanical garden that is the Amazon rainforest. Let's take a closer look at how Supersmart’s rainforest herbal supplements can help boost immune system support.

Who is the Wild Amazonian Formula Made For?

This exceptional formulation is intended for people over 50 years old, as older adults’ immune systems are generally weaker and slower to respond to infections and abnormal cellular events.

The Wild Amazonian formula is equally suitable for anyone whose health has been compromised by adverse health conditions, such as diabetes, cardiovascular problems, chronic stress or chemotherapy, as well as anyone who wants to minimize their risk of all kinds of infections.

These are the four biggest benefits it offers:

  • It stimulates the immune system and optimizes the body's natural self-healing mechanisms.
  • It increases the body’s resistance to adverse influences.
  • It produces a general tonic effect, especially following an illness or short-term health problem.
  • It combats stress, infections, fatigue and inflammation.

What Rainforest Herbal Supplements Are In the Wild Amazonian Formula?

The Amazon rainforest is an extraordinary source of rare plant species that possess amazing therapeutic properties. SuperSmart has carefully selected the best of them to produce an unprecedented synergistic formula. Three criteria have been applied in making our selection: the plants' empirical use, their clear, scientifically demonstrated physiological effects and their synergistic power.

Cat's Claw (Uncaria Tomentosa)

This is a vine native to the Amazon basin. It’s used by indigenous people for its immune-stimulating properties and the many studies that have been done in recent years have boosted its popularity.

A cat's claw supplement plays an important role in regulating programmed cell death, the process that makes abnormal cells commit suicide. Its high content of sterol compounds (beta-sitosterol, stigmasterol, campesterol), tannins and procyanidins is the most likely reason its uses are so well documented and have led to researchers exploring more cat's claw supplement uses.

Cat's claw also helps improve immune response, fight inflammation, boost the antioxidant system and repair damaged DNA. One clinical trial of 12 healthy subjects demonstrated its protective effect against mutations to DNA.

Suma Root (Pfaffia Paniculata)

Also known as 'Brazilian ginseng,' suma root is an adaptive plant from the Amazon basin. Suma root supplements have long been used by Olympic athletes to help build muscle and boost endurance without dealing with the unwelcome side-effects of steroids.

Pfaffia paniculata benefits are primarily linked to high beta-ecdysterone content, though it also contains saponins, glycosides and other compounds that enable it to slow down the proliferation of abnormal cells and generally aid the immune system.

Bark of Inner Lapacho (Pau D’arco)

Lapacho has traditionally been used to fight all kinds of infections and combat abnormal cell processes. Today, it is commonly used in Brazil to fight respiratory and skin infections, gastroenteritis and cystitis.

Scientists have identified two active ingredients responsible for lapacho’s positive effect on cellular health and its anti-proliferative properties: lapachol and beta-lapachone. Both are powerful, natural anti-inflammatories, but it’s the synergy between all its compounds that make it so effective.

Graviola Leaves (Corossolier)

This is a tropical Amazonian plant used in traditional medicine for its anti-proliferative properties. A number of studies have shown graviola is associated with optimizing mechanisms that stem the development of abnormal cell processes: inducing programmed cell death, selective inhibition, regulating receptors of growth factors and more.

It’s the plant's high alkaloid content, particularly reticulin and coreximine, that is responsible for this exceptional property. Graviola offers other benefits too: it contains enzymatic antioxidants, such as catalase and superoxide dismutase, both of which combat oxidative stress.

Mullaca (Physalis Angulata)

In folk-medicine, the mullaca supplement is used to treat various problems, such as rheumatism and malaria. But this Amazon ground-cherry offers much more.

Researchers have demonstrated its ability to inhibit the growth of various abnormal cells, combat inflammation and positively modulate the immune response. The plant's high concentration of physalis — natural steroids with powerful anti-proliferative effects — that are responsible. It also contains phytosterols that have antioxidant properties and have positive effects on cardiovascular health.

How Does Wild Amazonian Boost the Immune System?

The natural plant extracts in the Wild Amazonian Formula are well-known to tribes of the Amazon rainforest, particularly the Ashaninka and Campo, who believe they affect both mind and body.

They have been used in Amazonia for thousands of years. Given that traditional medicine rarely “gets it wrong,” thousands of researchers have set out to scientifically test the virtues attributed to these plants.

The anti-inflammatory, immune-stimulant and anti-proliferative properties of these plants have successfully been demonstrated and explained in a laboratory setting. A well-managed combination of these plants can help ward off infections and relieve problems often held in check by conventional medicine. It can, above all, help to stimulate the immune system through several distinct mechanisms:

  • Protecting cells against oxidants known to damage cell organelles, membranes and DNA
  • Disrupting replication of viruses and thus preventing their progress within the body
  • Stimulating the interleukin-1 group of cytokines, which facilitate the transmission of white cells to infection sites
  • Fighting inflammation by inhibiting the production of “pro-inflammatory” prostaglandins and suppressing the activity of TNF, a cytokine involved in chronic inflammation
  • Improving cell oxygenation
  • Repairing errors and mutations to DNA
  • Slowing down or inhibiting abnormal cell proliferation

5 Good Reasons To Start Taking Wild Amazonian Now

The Wild Amazonian is one of the best cat's claw supplements and one of the best suma root supplements available. Here are five reasons you should consider taking it now:

  1. The plants in our rainforest herbal supplements are all wild-growing species and are hand-picked. They are much more active than their cultivated equivalents because they're subject to different natural stresses and are completely uncontaminated by pesticides.
  2. Large-scale scientific studies support the use of the five plants contained in this formula for self-healing.
  3. These plants have been used for thousands of years because of their high content of exceptional micronutrients.
  4. They all help stimulate the immune system and optimize the body's natural self-healing mechanisms.
  5. With different mechanisms of action, they offer maximum synergy.

Does Wild Amazonian Have Any Contraindications?

The Wild Amazonian Formula is not recommended for those suffering from auto-immune diseases, as stimulating the immune system in these individuals may threaten, instead of protecting. In addition, some of the herbs, particularly mullaca, can produce a mild hypotensive and anticoagulant effect.

Composition
Daily dose: 4 capsules
Number of doses per pack: 30
Amount per dose
4:1 extract of suma root (Pfaffia paniculata) 400 mg *
4:1 extract of cat’s claw bark (Uncaria tomentosa) 400 mg *
4:1 extract of graviola leaves (Annona muricata) 400 mg *
4:1 extract of pau d’arco (Tabebuia impetiginosa) 300 mg *
Mullaca powder (Physalis angulata) 300 mg *
Other ingredients: acacia gum, white rice flour.
*Wild-growing, hand-picked plants.
Directions for use

How To Take Amazonian Formula Capsules

If you are looking for an herbal supplement that will help you self-heal, this anti-aging supplement might be right for you. Our rainforest herbal supplements come with the following recommendations:

  • Get the right amount of sleep for your needs (7 hours a night is often the minimum required).
  • Don't smoke and try to use household products that contain few chemicals.
  • Always wash your fruit and vegetables or make sure you choose organic varieties.
  • Regularly exercise.
  • Eat a healthy diet with immune-stimulant foods, such as mushrooms, garlic, onions and shallots.

Wild Amazonian Formula can be combined with other supplements available to buy at Supersmart, such as Reishi extract or Adaptix to maximize its effects on immunity, or with Nicotinamide Mononucleotide 125 mg to add powerful anti-aging effects. To prevent winter infections, it's best to begin a six-month course of supplementation in the autumn. In all other cases, it can be continued for longer.

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Mon mari tombait toujours malade (maux de gorge et états grippaux). Les rechutes ont été beaucoup moins fréquentes.
References
  1. Sandoval M, Chaarbonnett RM, Okuhama NN, Roberts J, Krenova Z, Trentacosti AM, et al. Cat’s claw inhibits TNFa production and scavenges free radicals: role in cytoprotection. Free Rad Biol Med 2000;29(1):71–8.
  2. Desmarchelier C, Mongelli E, Coussio J, Ciccia G. Evaluation of the in vitro antioxidant activity in extracts of Uncaria tomentosa (Willd.)DC. Phytotherpay Res 1998;11(3):254–6.
  3. Sandoval-Chacon M, Thompson JH, Zhang X-J, Liu X, Mannick EE, Sadowska-Krowicka H, et al. Antiinflammatory action of cat’s claw: the role of NF-kB. Aliment Pharmacol Therapy 1998;12:1279–89.
  4. Hardin, S. R. (2007). Cat’s claw: An Amazonian vine decreases inflammation in osteoarthritis. Complementary Therapies in Clinical Practice, 13(1), 25–28. doi:10.1016/j.ctcp.2006.10.003
  5. Sheng Y, Li L, et al. DNA repair enhancement of aqueous extracts of Uncaria tomentosa in a human volunteer study.Phytomedicine 2001 Jul;8(4):275-82.
  6. Li J, Jadhav AN, Khan IA. Triterpenoids from Brazilian ginseng, Pfaffia paniculata. Planta Med. 2010 Apr;76(6):635-9. doi: 10.1055/s-0029-1240631. Epub 2009 Nov 25.
  7. Pinello KC, Fonseca Ede S, Akisue G, Silva AP, Salgado Oloris SC, Sakai M, Matsuzaki P, Nagamine MK, Palermo Neto J, Dagli ML. Effects of Pfaffia paniculata (Brazilian ginseng) extract on macrophage activity. Life Sci. 2006 Feb 16;78(12):1287-92. Epub 2005 Oct 7.
  8. da Silva TC, Cogliati B, da Silva AP, Fukumasu H, Akisue G, Nagamine MK, Matsuzaki P, Haraguchi M, Górniak SL, Dagli ML. Pfaffia paniculata (Brazilian ginseng) roots decrease proliferation and increase apoptosis but do not affect cell communication in murine hepatocarcinogenesis. Exp Toxicol Pathol. 2010 Mar;62(2):145-55. doi: 10.1016/j.etp.2009.03.003. Epub 2009 May 9.
  9. Kee, J.-Y., Han, Y.-H., Park, J., Kim, D.-S., Mun, J.-G., Ahn, K. S., … Hong, S.-H. (2016). β-Lapachone Inhibits Lung Metastasis of Colorectal Cancer by Inducing Apoptosis of CT26 Cells. Integrative Cancer Therapies, 16(4), 585–596. doi:10.1177/1534735416681638
  10. Kee, J.-Y., Han, Y.-H., Kim, D.-S., Mun, J.-G., Park, S.-H., So, H.-S., … Hong, S.-H. (2017). β-Lapachone suppresses the lung metastasis of melanoma via the MAPK signaling pathway. PLOS ONE, 12(5), e0176937. doi:10.1371/journal.pone.0176937
  11. Lee, E.-J., Ko, H.-M., Jeong, Y.-H., Park, E.-M., & Kim, H.-S. (2015). β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia. Journal of Neuroinflammation, 12(1). doi:10.1186/s12974-015-0355-z
  12. JEON, Y.-J., BANG, W., SHIN, J.-C., PARK, S.-M., CHO, J.-J., CHOI, Y. H., … CHAE, J.-I. (2015). Downregulation of Sp1 is involved in β-lapachone-induced cell cycle arrest and apoptosis in oral squamous cell carcinoma. International Journal of Oncology, 46(6), 2606–2612. doi:10.3892/ijo.2015.2972
  13. Shankar Babu, M., Mahanta, S., Lakhter, A. J., Hato, T., Paul, S., & Naidu, S. R. (2018). Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2. PLOS ONE, 13(2), e0191419. doi:10.1371/journal.pone.0191419
  14. Son, Y.-R., Choi, E.-H., Kim, G.-T., Park, T.-S., & Shim, S.-M. (2016). Bioefficacy of Graviola leaf extracts in scavenging free radicals and upregulating antioxidant genes. Food & Function, 7(2), 861–871. doi:10.1039/c5fo01258a
  15. Torres, M. P., Rachagani, S., Purohit, V., Pandey, P., Joshi, S., Moore, E. D., … Batra, S. K. (2012). Graviola: A novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism. Cancer Letters, 323(1), 29–40. doi:10.1016/j.canlet.2012.03.031
  16. Yang, C., Gundala, S. R., Mukkavilli, R., Vangala, S., Reid, M. D., & Aneja, R. (2015). Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves confer protection against prostate cancer. Carcinogenesis, 36(6), 656–665. doi:10.1093/carcin/bgv046
  17. Qazi, A. K., Siddiqui, J. A., Jahan, R., Chaudhary, S., Walker, L. A., Sayed, Z., … Macha, M. A. (2018). Emerging therapeutic potential of graviola and its constituents in cancers. Carcinogenesis, 39(4), 522–533. doi:10.1093/carcin/bgy024
  18. Sun, C.-P., Qiu, C.-Y., Yuan, T., Nie, X.-F., Sun, H.-X., Zhang, Q., … Qiu, F. (2016). Antiproliferative and Anti-inflammatory Withanolides from Physalis angulata. Journal of Natural Products, 79(6), 1586–1597. doi:10.1021/acs.jnatprod.6b00094
  19. Farias IL, Araújo MC, Farias JG, et al. Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:892182. doi:10.1155/2012/892182
  20. Nagamine MK, da Silva TC, Matsuzaki P, et al. Cytotoxic effects of butanolic extract from Pfaffia paniculata (Brazilian ginseng) on cultured human breast cancer cell line MCF-7. Exp Toxicol Pathol. 2009;61(1):75-82. doi:10.1016/j.etp.2008.01.017
  21. de Miranda FG, Vilar JC, Alves IA, Cavalcanti SC, Antoniolli AR. Antinociceptive and antiedematogenic properties and acute toxicity of Tabebuia avellanedae Lor. ex Griseb. inner bark aqueous extract. BMC Pharmacol. 2001;1:6. doi:10.1186/1471-2210-1-6
  22. Rady I, Bloch MB, Chamcheu RN, et al. Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review. Oxid Med Cell Longev. 2018;2018:1826170. Published 2018 Jul 30. doi:10.1155/2018/1826170
  23. Osho A, Adetunji T, Fayemi SO, Moronkola DO. Antimicrobial activity of essential oils of Physalis angulata. L. Afr J Tradit Complement Altern Med. 2010;7(4):303-306. doi:10.4314/ajtcam.v7i4.56696

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