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Welcome Shop by health concern Tiredness and Lack of energy FlavoLife Flavonoids Supplement
FlavoLife Supplement
FlavoLife Supplement
0793FlavoLife SupplementSize
Sans nano-particulesSans glutenVegan
FlavoLife Flavonoids Supplement
Tiredness and Lack of energy
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FlavoLife is an ‘all-in-one’, health-supporting flavonoids formulation for the most discerning consumer:

  • Contains nine exceptional bioflavonoids, all extracted from plant species.
  • Incorporates all categories of the flavonoids family.
  • Developed using the latest scientific research (2019 ECU study).
  • Helps reduce the risk of chronic disease.
  • Provides a whole host of other positive health effects (antioxidant, anti-inflammatory, anxiolytic, anti-stroke, anti-varicose, neuroprotective and more).
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60 Veg. Caps.
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Flavonoid chemical structure


FlavoLife is a flavonoids supplement that’s been developed using the latest scientific research (in particular, this 2019 ECU study.) In line with recent scientific recommendations, it contains 9 bioflavonoids and includes all the categories in the large flavonoids family.

What health benefits can you expect from taking FlavoLife?

FlavoLife is designed to improve many aspects of general health, including cardiovascular and blood circulation problems, weak immunity, stress and anxiety and neuro-inflammation. FlavoLife has been developed to reflect the findings of multiple scientific studies, the latest of which was published in 2019.

Researchers at Edith Cowan University discovered a strong correlation between flavonoids intake and lower risk of mortality from cancer and cardiovascular disease. Their conclusion was clear: the protective effect is highest when intake exceeds 500 mg a day, though variety may be as important as quantity.

This major 2019 study was so groundbreaking — adding to existing findings from hundreds of recent studies on flavonoids, that we felt compelled to introduce this exceptional flavonoids supplement, unprecedented on the market, designed to improve numerous aspects of your health.

Lead researcher, Dr. Nicola Bondonno, had this to say about the results: “These findings are important as they highlight the potential to prevent cancer and heart disease by encouraging the consumption of flavonoid-rich foods, particularly in people at high risk of these chronic diseases,” She added that diversity is as significant as the number of flavonoids consumed: “It’s very important to consume several types of flavonoids by eating as wide a variety as possible of the foods that contain them.”

Diversity is key because each flavonoids compound has a slightly different mechanism of action, and contributes synergistically to a whole host of health benefits, including:

  • Antioxidant effects — their hydroxyl grouping means they can quench and stabilize free radicals
  • Anti-inflammatory effects — flavonoids have an inhibitory effect on inflammatory enzymes, such as cyclooxygenase and lipoxygenase
  • Anti-atherosclerosis effects — specifically by reducing oxidation of LDL cholesterol transporters
  • Improvements in capillary permeability and circulation — flavonoids affect blood vessels through vitamin P activity
  • Anti-angiogenesis effects
  • Anxiolytic, soothing and neuro-protective effects
  • Decreased risk of many chronic ‘diseases of civilization’ — cardiovascular diseases, diabetes, cancer, stroke, etc.

What are flavonoids, exactly?

Flavonoids are compounds found in the plant kingdom and are usually consumed in the form of fruits, vegetables, tea and wine. This large group of molecules comprises more than 6,000 natural compounds that exert a wide range of biological activity.

Research into flavonoids has increased significantly since the discovery of the ‘French Paradox,’ in which a correlation was observed among the French population between moderate consumption of red wine and saturated fats and a relatively low rate of death from cardiovascular causes.

What bioflavonoids are in FlavoLife?

FlavoLife contains the most effective flavonoids and covers all the categories of this large family of compounds — flavonols, flavones, flavanones, flavan-3-ols and anthocyanidins:

  • Fisetin —extracted from the stems of Toxicodendron succedaneum. It has been described as offering a number of beneficial biological effects, including inhibition of cell proliferation and inflammation, neuroprotection and bone protection. But its two most extraordinary properties of the best fisetin supplement is its ability to destroy senescent cells which parasitize the body, and activate the mechanism of autophagy whereby cells digest their own waste. Several studies have shown this helps extend longevity and reduce markers of senescence in humans.
  • Quercetin — extracted from Sophora Japonica buds. Like rutin, a quercetin supplement has antioxidant, anti-inflammatory, vaso-protective (blood vessel protection) and anti-thrombotic (blood clot prevention) properties, according to studies.
  • Hesperidin — extracted from sweet orange. This primarily helps to maintain blood vessel integrity and strengthen the capillary network, according to research.
  • Myricetin — extracted from the bark of Myrica rubra. This flavonol is recognized through studies for reducing both the risk of cardiovascular problems and levels of chronic inflammation.
  • Rutin — also extracted from Sophora Japonica buds. This is an exceptional antioxidant flavonoid; the main effect, according to some studies, is to reduce capillary fragility and permeability.
  • Oligo-proanthocyanidins — extracted from grape seeds. These antioxidant flavonoids have 20 times greater activity than Vitamin E and are active in both aqueous and lipid environments. They have the specific property of binding to collagen and thus help maintain the structural integrity of connective tissue.
  • Luteolin — also extracted from Sophora Japonica buds. By countering the release of pro-inflammatory cytokines, luteolin has been shown to fight inflammation, particularly in the brain.
  • EGCG — extracted from green tea. This is the main compound in the catechin family: it has anti-inflammatory effects and helps inhibit angiogenesis, a process of neovascularization which occurs in various pathophysiological situations.
  • Apigenin — extracted from celery seeds. This anti-inflammatory flavone helps relax the arteries and produces anxiolytic effects (it binds to central benzodiazepine receptors).

Quercetin and Fisetin, Plus Four Other Reasons To Support Your Health with FlavoLife

.FlavoLife contains two of the best natural senolytic compounds: quercetin and fisetin. The quercetin benefits and reasons to use a fisetin supplement have been outlined above, but there are four more reasons to choose Supersmart’s flavonoids supplement.

  1. Studies show that flavonoids enhance the action of several other micronutrients, particularly Vitamin C, by increasing absorption and delaying elimination by the body.
  2. FlavoLife combines nine of the most active flavonoids because, between them, they produce synergistic effects.
  3. FlavoLife compensates for low flavonoids consumption from dietary sources. Flavonoids are found in many fruits and vegetables, but changes in lifestyle have led to a sharp decline in their consumption. It’s no coincidence the use of flavonoid-containing extracts continues to rise.
  4. The effects are long-lasting. Certain flavonoids, such as quercetin, have a particularly long life in the body, enabling them to work in a diffuse way over time, with no side effects.
Daily dose: 2 capsules
Number of doses per pack: 30
Amount per dose
Rutin (from extract of Sophora japonica buds) 150 mg
Hesperidin (from extract of Citrus sinensis fruit) 150 mg
Myricetin (from extract of Myrica rubra bark) 100 mg
Luteolin (from extract of Sophora japonica buds) 100 mg
Oligomeric proanthocyanidins (from grape seed extract) 100 mg
Quercetin (from extract of Sophora japonica buds) 80 mg
Epigallocatechin gallate (EGCG) (from green tea) 50 mg
Fisetin (from extract of Rhus succedanea stems) 30 mg
Apigenin (from extract of celery seeds) 30 mg
Other ingredients: acacia gum, white rice flour.
Directions for use

how should FlavoLife Capsules Be Taken?

Supersmart recommends taking two FlavoLife capsules daily, and always with a meals. It can be combined with other supplements available to buy in our catalog such as Daily 3. And if you’re particularly interested in FlavoLife for its vascular benefits (venous insufficiency), it is better combined with a supplement containinghorse chestnut extract. After flavonoids pass through the colon, they are reabsorbed and affect several biological functions, including protein synthesis, cell differentiation and proliferation and angiogenesis. Deciding where to buy a flavonoids supplement should be an easy decision. Buy FlavoLife capsules from Supersmart.
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  1. Bondonno NP, Dalgaard F, Kyrø C, et al. Flavonoid intake is associated with lower mortality in the Danish Diet Cancer and Health Cohort. Nat Commun. 2019;10(1):3651. Published 2019 Aug 13. doi:10.1038/s41467-019-11622-x
  2. Ferrières J. The French paradox: lessons for other countries. Heart. 2004;90(1):107-111. doi:10.1136/heart.90.1.107
  3. Khan N, Syed DN, Ahmad N, Mukhtar H. Fisetin: a dietary antioxidant for health promotion. Antioxid Redox Signal. 2013;19(2):151-162. doi:10.1089/ars.2012.4901
  4. Li Y, Yao J, Han C, et al. Quercetin, Inflammation and Immunity. Nutrients. 2016;8(3):167. Published 2016 Mar 15. doi:10.3390/nu8030167
  5. Hajialyani M, Hosein Farzaei M, Echeverría J, Nabavi SM, Uriarte E, Sobarzo-Sánchez E. Hesperidin as a Neuroprotective Agent: A Review of Animal and Clinical Evidence. Molecules. 2019;24(3):648. Published 2019 Feb 12. doi:10.3390/molecules24030648
  6. Semwal DK, Semwal RB, Combrinck S, Viljoen A. Myricetin: A Dietary Molecule with Diverse Biological Activities. Nutrients. 2016;8(2):90. Published 2016 Feb 16. doi:10.3390/nu8020090
  7. Ganeshpurkar A, Saluja AK. The Pharmacological Potential of Rutin. Saudi Pharm J. 2017;25(2):149-164. doi:10.1016/j.jsps.2016.04.025
  8. Fine AM. Oligomeric proanthocyanidin complexes: history, structure, and phytopharmaceutical applications. Altern Med Rev. 2000;5(2):144-151.
  9. Lin Y, Shi R, Wang X, Shen HM. Luteolin, a flavonoid with potential for cancer prevention and therapy. Curr Cancer Drug Targets. 2008;8(7):634-646. doi:10.2174/156800908786241050
  10. Du GJ, Zhang Z, Wen XD, et al. Epigallocatechin Gallate (EGCG) is the most effective cancer chemopreventive polyphenol in green tea. Nutrients. 2012;4(11):1679-1691. Published 2012 Nov 8. doi:10.3390/nu4111679
  11. Salehi B, Venditti A, Sharifi-Rad M, et al. The Therapeutic Potential of Apigenin. Int J Mol Sci. 2019;20(6):1305. Published 2019 Mar 15. doi:10.3390/ijms20061305
  12. McAnulty SR, Nieman DC, McAnulty LS, Lynch WS, Jin F, Henson DA. Effect of mixed flavonoids, n-3 fatty acids, and vitamin C on oxidative stress and antioxidant capacity before and after intense cycling. Int J Sport Nutr Exerc Metab. 2011;21(4):328-337. doi:10.1123/ijsnem.21.4.328

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FlavoLife Flavonoids Supplement
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